| 2021-10-01 | Morning Report: Storylines to Watch in Week 4 vs. Seahawks |
| 2021-10-01 | 49ers WRs, RBs Get 'Highly Favorable' Matchup vs. Seahawks in Week 4 |
| 2021-10-01 | George Kittle, Elijah Mitchell Questionable; Josh Norman Doubtful vs. Seahawks |
| 2021-10-01 | Takeo Spikes Has One Challenge for Jimmy Garoppolo, 49ers Offense vs. Seahawks |
| 2021-10-02 | 49ers PREP Selects Caleb Womack as Player of the Week |
| 2021-10-02 | 49ers PREP Selects Greg Haubner as Coach of the Week |
| 2021-10-02 | 49ers Recibe a Seahawks Para El Primer Encuentro Divisional de la Temporada 2021 |
| 2021-10-03 | George Kittle Active; Elijah Mitchell, Josh Norman OUT vs. Seahawks |
| 2021-10-03 | Deebo Samuel Honors Late Tommy ‘Tiny’ Lister With Gameday Entrance |
| 2021-10-03 | Seattle Seahawks vs. San Francisco 49ers Week 4 Live Blog |
| 2021-10-03 | Robbie Gould Questionable to Return vs. Seahawks |
| 2021-10-03 | Trey Lance Starts 2nd Half as Jimmy Garoppolo Suffers Calf Injury |
| 2021-10-03 | Deebo Samuel Notches Third-Straight 100-yard Game vs. Seahawks |
| 2021-10-04 | ‘Some Good, Some Bad’ in Trey Lance’s Week 4 Outing vs. Seahawks |
| 2021-10-04 | What Went Wrong in 49ers Week 4 Loss to Seahawks |
| 2021-10-04 | 49ers Adapt Gameplan as Injuries Arise vs. Seahawks |
| 2021-10-04 | What the 49ers and Seahawks Had to Say Following Week 4 |
| 2021-10-04 | Morning Report: Recapping 49ers vs. Seahawks in Week 4 |
| 2021-10-04 | 49ers Foundation Celebrates First $1 Million Pledged Through Annual Giving Society |
| 2021-10-04 | 49ers Catch a Big Break With News on Garoppolo, Williams and Others |
| 2021-10-05 | Dura Derrota Divisional vs. Seahawks |
| 2021-10-05 | 75 for 75: 'The Gold Rush' Sack Attack |
| 2021-10-05 | WON Monthly Magazine October 2021 |
| 2021-10-05 | 49ers Sign K Joey Slye; Add Three Players to Practice Squad |
| 2021-10-06 | Morning Report: Robbie Gould Lands on IR, 49ers Sign Kicker |
| 2021-10-06 | 49ers Welcome Visual Edge IT AS Organization's #CyberFit Delivery Partner |
| 2021-10-06 | Cuatro Downs: El Reto Mas Grande Para Ambos 49ers y Cardinals en la Semana 5 |
| 2021-10-06 | Four Downs: Biggest Challenge for Both 49ers, Cardinals in Week 5 |
| 2021-10-07 | Morning Report: Two 49ers Land on PFF's First-Quarter All-Pro Team |
| 2021-10-07 | 75 for 75: 63-Yard Field Goal |
| 2021-10-07 | Ways to Watch and Listen to 49ers vs. Cardinals in Week 5 |
| 2021-10-07 | Trey Lance Sees Starting Reps But Door Isn’t Closed on Jimmy G for Week 5 |
| 2021-10-08 | Jimmy G to Test Calf in Final Practice Ahead of Week 5 vs. Cardinals |
| 2021-10-08 | Morning Report: NFL.com Believes 49ers are 'Contenders' Despite 2-2 Start |
| 2021-10-08 | 75 for 75: Kap Unleashed |
| 2021-10-08 | Is Trey Lance a Top-10 Fantasy QB in Week 5? |
| 2021-10-08 | Trey Lance to Make First Start with Garoppolo OUT, Kittle on IR |
| 2021-10-09 | Steve Young and Others Eager to 'See More' from Trey Lance in Week 5 |
| 2021-10-09 | 49ers Announce Roster Moves Ahead of Week 5 |
| 2021-10-10 | 49ers PREP Selects C.J. Anderson as Coach of the Week |
| 2021-10-10 | 49ers PREP Selects Elijah La Guardia as Player of the Week |
| 2021-10-10 | 49ers Viajan Hacia Arizona Para Su Segundo Enfrentamiento Divisional Consecutivo |
| 2021-10-10 | Jimmy Garoppolo Spotted Working Out at State Farm Stadium 👀 |
| 2021-10-10 | Elijah Mitchell, Josh Norman Active; Who's In, Who's Out vs. Cardinals |
| 2021-10-10 | San Francisco 49ers vs. Arizona Cardinals Week 5 Live Blog |
| 2021-10-10 | Assessing Trey Lance's First Half vs. Cardinals |
| 2021-10-11 | 49ers Get Aggressive in Trey Lance First Start But Not Enough vs. Cards |
| 2021-10-11 | Morning Report: Recapping 49ers vs. Cardinals in Week 5 |
| 2021-10-11 | What the 49ers and Cardinals Had to Say Following Week 5 |
| 2021-10-11 | San Francisco Pierde Un Juego Cerrado En Arizona |
| 2021-10-11 | 75 for 75: From Typist to Team President |
| 2021-10-11 | 49ers, Cardinals React to Trey Lance’s First NFL Start |
| 2021-10-11 | 49ers Activate CB Davontae Harris from IR; Release CB Buster Skrine |
| 2021-10-11 | Grading Trey Lance and Other 49ers Of Note in Week 5 vs. Cardinals |
| 2021-10-11 | Trey Lance Suffers Knee Sprain, Could Miss 1-2 Weeks |
| 2021-10-12 | 75 for 75: From Gridiron to Boxing Ring |
| 2021-10-12 | 49ers Waive Two Players |
| 2021-10-12 | Is the 49ers Toughest Stretch of 2021 Behind Them? |
| 2021-10-13 | 75 for 75: Golf Links and Gridirons |
| 2021-10-15 | 75 for 75: 711 Nevada Street |
| 2021-10-15 | 49ers PREP Selects Doug Longero as Coach of the Week |
| 2021-10-15 | 49ers PREP Selects Jayden Hall as Player of the Week |
| 2021-10-18 | 49ers Sign LB Mychal Kendricks; Make a Series of Other Moves |
| 2021-10-18 | No Sign of Trey Lance; Jimmy G and Other 49ers Re-emerge at Practice |
| 2021-10-19 | Morning Report: Jimmy Garoppolo Returns to Practice |
| 2021-10-19 | Los 49ers Regresan A La Acción |
| 2021-10-20 | Morning Report: 49ers Discuss Mindset Heading into Week 7 |
| 2021-10-20 | 49ers Aim to Define Their Identity Following Timely Bye |
| 2021-10-20 | 75 for 75: Rookie TE Pins LT |
| 2021-10-20 | 49ers 'Pretty Optimistic' in Jimmy G's Return Ahead of Colts |
| 2021-10-21 | Morning Report: Will Jimmy G Be Ready for 'Sunday Night Football'? |
| 2021-10-21 | 75 for 75: Tight End Tenacity |
| 2021-10-22 | DeFo, Jonathan Taylor and Areas of Concern for 49ers, Colts in Week 7 |
| 2021-10-22 | Week 7 Conditions Make a Perfect Fantasy Setup for Deebo Samuel vs. Colts |
| 2021-10-22 | Trey Lance OUT, Trent Williams Doubtful ahead of Primetime Matchup vs. Colts |
| 2021-10-23 | Ways to Watch and Listen to 49ers vs. Colts in Week 7 |
| 2021-10-23 | 49ers Vuelven a Casa Para Enfrentar a Colts Despues De Su Semana De Descanso |
| 2021-10-23 | 49ers Make a Series of Roster Moves ahead of Week 7 |
| 2021-10-24 | Four Critical Areas of Focus for 49ers in Week 7 vs. Colts |
| 2021-10-25 | San Francisco 49ers vs. Indianapolis Colts Week 7 Live Blog |
| 2021-10-25 | Downpour Metaphorically Describes 49ers Disappointing 30-18 Loss to Colts |
| 2021-10-25 | 49ers PREP Selects Devon Rivers as Player of the Week |
| 2021-10-25 | 49ers PREP Selects Denny Molzen as Coach of the Week |
| 2021-10-25 | 75 for 75: First NFL Playoff Win |
| 2021-10-25 | PFF Pins Warner, Mitchell, Al-Shaair as Few Positives from Week 7 Loss |
| 2021-10-25 | 49ers Activate DL from Reserve/Suspended List; Sign S to Practice Squad |
| 2021-10-25 | Errores Costosos En Un Día Lluvioso Para Los 49ers Contra Los Colts |
| 2021-10-26 | Kyle Shanahan Sticking with Jimmy G as 49ers Expect Trey Lance's Return |
| 2021-10-26 | Morning Report: Trey Lance Expected at Practice ahead of Bears |
| 2021-10-26 | 75 for 75: Bears Weather Game |
| 2021-10-27 | Not All is Lost in 49ers Search to Get Back on Track, Here's Why |
| 2021-10-27 | 75 for 75: Let the Watters Run |
| 2021-10-28 | Morning Report: Why 49ers Can Still Turn Around 2021 Season |
| 2021-10-28 | 75 for 75: T.O.’s Reception Redemption |
| 2021-10-28 | Ways to Watch and Listen to 49ers vs. Bears in Week 8 |
| 2021-10-28 | Ganar en Chicago Podría Cambiar la Perspectiva de 49ers por el Resto de la Temporada |
| 2021-10-29 | How Success in Chicago Can Change 49ers Perspective on Rest of Season |
| 2021-10-29 | Morning Report: Previewing 49ers at Bears in Week 8 |
| 2021-10-29 | 75 for 75: Postseason Rush |
| 2021-10-29 | Is 49ers D a Top Fantasy Option vs. Justin Fields and Co. in Week 8? |
| 2021-10-29 | 49ers Viaja a Chicago para Enfrentarse a los Bears en la Semana 8 |
| 2021-10-29 | Trent Williams Returns to Practice ahead of Bears; Javon Kinlaw to Go on IR |
| 2021-10-30 | Two 49ers Downgraded to OUT vs. Bears; Other Roster Moves |
| 2021-10-31 | A Look at Who's In and Who's Out in Week 8 Matchup vs. Bears |
| 2021-10-31 | Live Blog: San Francisco 49ers vs. Chicago Bears |
| 2021-10-31 | A Tale of Two Halves; Takeaways from 49ers 33-22 Win Over the Bears |
| 2021-10-31 | Samuel and Mitchell Making Moves in 49ers Record Books |
