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San Francisco 49ers head coach Kyle Shanahan discussed DL Nick Bosa's calf injury, addressed the team's continued challenges at defensive line, and previewed Sunday's Week 3 matchup against the Arizona Cardinals.

Check out the best moments from practice as the 49ers prepare for the Week 3 matchup against the Arizona Cardinals

San Francisco 49ers TE George Kittle, WR Deebo Samuel Sr., T Trent Williams, and FB Kyle Juszczyk expressed confidence in QB Brock Purdy's composure and mentality, and discussed the challenges of facing a familiar opponent in the Arizona Cardinals.

San Francisco 49ers QB Brock Purdy reflected on his Week 2 performance, discussed the challenges the Arizona Cardinals defense presents, and praised the offensive line for putting together consecutive games without allowing a sack.

San Francisco 49ers defensive coordinator Raheem Morris highlighted the team's next-man-up mentality and praised LB Fred Warner's decision-making and CB Upton Stout's physicality, while offensive coordinator Klay Kubiak detailed Brock Purdy's standout performance in Week 2 and how the offense is preparing for the Arizona Cardinals this Sunday.

The San Francisco 49ers improve to 2-0 following a 35-13 win over the Miami Dolphins. Brooke Evans and Aubrie Tolliver break down the home opener, hear from FOX Sports reporter Allison Williams, and welcome Cardinals team reporter Dani Sureck to preview the Week 3 NFC West matchup.

San Francisco 49ers RB Christian McCaffrey broke down the offense's focus on consistency and complementary football, WR Brandin Cooks discussed the appeal of joining San Francisco's veteran roster, and LB Fred Warner previewed the challenge of going against the Cardinals.

Take a look back at some of the best photos from the 49ers matchups against the Cardinals throughout the years.

San Francisco 49ers head coach Kyle Shanahan discussed QB Brock Purdy earning NFC Offensive Player of the Week honors, addressed the team's depth at defensive tackle, and previewed Sunday's Week 3 matchup against the Arizona Cardinals.

Broadcast and streaming information for the San Francisco 49ers Week 3 matchup against the Arizona Cardinals at Levi's® Stadium.

Kyle Shanahan joined a media call following the 49ers Week 2 win over the Miami Dolphins to provide injury updates and discuss QB Brock Purdy's performance.

Explore the 49ers Latino Heritage Collection, a special capsule dedicated to celebrating culture, unity, pride and the spirit of community throughout California.