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San Francisco 49ers DL Sebastian Valdez takes down Seattle Seahawks QB Sam Darnold for his first career NFL sack in Week 5 of the 2026 NFL season.

San Francisco 49ers LB Jaden Dugger takes down Seattle Seahawks QB Sam Darnold for his first career NFL sack in Week 5 of the 2026 NFL season.

San Francisco 49ers QB Brock Purdy delivers a two-yard touchdown pass to WR Mike Evans against the Seattle Seahawks.

San Francisco 49ers CB Renardo Green intercepts Seattle Seahawks QB Sam Darnold's pass in Week 5 of the 2026 NFL season.

San Francisco 49ers first-round pick in 2025, DL Mykel Williams, makes a return against the Seattle Seahawks after nearly a year off the field.

View pregame photos from the San Francisco 49ers Week 5 matchup vs. the Seattle Seahawks at Levi's® Stadium.

Take a look at players who have been ruled out for the San Francisco 49ers Week 5 matchup versus the Seattle Seahawks.

View photos as the team arrived to the locker room for their Week 5 matchup against the Seattle Seahawks, presented by Levi's®.

Check out some of the top photos as the 49ers travel to Seattle to take on the Seahawks, presented by United Airlines.

The 2026 Invasion Tour made a stop in Seattle, Washington, to rally against the Seahawks in Week 5.

Guy Haberman sits down with 49ers radio analyst Tim Ryan, now in his 13th season with the team, to preview the Week 5 matchup against the Seahawks and look back on a career that has spanned USC, the NFL, Fox, and SiriusXM.

The San Francisco 49ers released their latest injury updates headed into their contest against the Seattle Seahawks.

San Francisco 49ers head coach Kyle Shanahan provided several injury updates, discussed the activation of DL Mykel Williams, and broke down the keys to improving the run game ahead of Sunday's divisional matchup.

San Francisco 49ers T Trent Williams, TE George Kittle, OL Colton McKivitz, WR Deebo Samuel Sr., and DB Deommodore Lenoir discussed the challenge of playing in one of the league's most competitive road environments, praised WR Mike Evans' performance through a rib injury, and previewed Sunday's matchup against the Seahawks defense.

Guy Haberman sits down with 49ers radio analyst Tim Ryan, now in his 13th season with the team, to preview the Week 5 matchup against the Seahawks and look back on a career that has spanned USC, the NFL, Fox, and SiriusXM.

In Part 2 of You've Got Mail, presented by Delta Dental, 49ers OL Jake Brendel and OL Colton McKivitz reveal offensive line superstitions, answer fan questions, and take on the You've Got Mail wheel.

The San Francisco 49ers improve to 4-0 following a 24-14 win over Denver. Brooke Evans and Aubrie Tolliver break down the victory with beat reporter Cam Inman, hear from DB Siran Neal postgame, and welcome Seahawks team reporter John Boyle to preview the Week 5 NFC West matchup.

49ers OL Jake Brendel and Colton McKivitz join You've Got Mail to talk the offensive line's strong start, their first impressions of each other, and life off the field. Stay tuned for Part 2 featuring fan questions and the You've Got Mail wheel.

Cancer warrior Mo Pinkerton and his mother reflect on his cancer journey and special Crucial Catch experience with 49ers QB Mac Jones, from painting together to walking into Levi's® Stadium side by side on gameday.

San Francisco 49ers WR Deebo Samuel Sr. shows his support for Bay Area sports at the Valkyries historic playoff win.

Take a look at the personalized details of the 49ers and cancer warriors custom denim jackets gifted by Levi's®.

More than 1,000 Faithful came together to celebrate 80 seasons of 49ers football and 35 years of Foundation impact, empowering Bay Area youth and beyond, presented by SAP.