| 2010-12-01 | El Juego Terrestre Se Pone En Marcha |
| 2010-12-01 | First Look: Green Bay Packers |
| 2010-12-01 | Singletary's Notebook: Dec. 1 |
| 2010-12-01 | Opposite Spectrums |
| 2010-12-02 | 49ers Honor Community QBs |
| 2010-12-02 | Spikes Livens Up 49ers Defense |
| 2010-12-03 | 49ers Announce December CR Events |
| 2010-12-03 | Teams Talk: Maragos on Green Bay |
| 2010-12-03 | Singletary's Notebook: Dec. 3 |
| 2010-12-05 | Points of the Game: Packers |
| 2010-12-05 | 49ers Freeze Up in Green Bay |
| 2010-12-06 | Los 49ers Se Congelan En Green Bay |
| 2010-12-06 | Singletary's Notebook: Dec. 6 |
| 2010-12-07 | Second Look: Seattle Seahawks |
| 2010-12-08 | Smith Takes Big Leap in Secondary |
| 2010-12-08 | Singletary's Notebook: Dec. 8 |
| 2010-12-08 | 49ers Spread Holiday Spirit |
| 2010-12-08 | Alex Smith Gets Back in the Saddle |
| 2010-12-09 | Josh's Journal: Staying Positive |
| 2010-12-09 | Battle of Beast Modes |
| 2010-12-10 | Teams Talk: Lee on Seattle |
| 2010-12-10 | Singletary's Notebook: Dec. 10 |
| 2010-12-12 | Points of the Game: Seahawks |
| 2010-12-12 | 49ers Pick Off Seahawks 40-21 |
| 2010-12-12 | Smith Steps Up in Win |
| 2010-12-13 | Singletary's Notebook: Dec. 13 |
| 2010-12-13 | Los 49ers Arrebatan a Los Seahawks la Victoria 40-21 |
| 2010-12-13 | Smith Luce en la Victoria |
| 2010-12-14 | First Look: San Diego Chargers |
| 2010-12-14 | Smith Prepares for Homecoming |
| 2010-12-15 | Brunner's Blog: Bowl Season |
| 2010-12-15 | The Man in the Middle |
| 2010-12-16 | Teams Talk: Reed on San Diego |
| 2010-12-16 | Points of the Game: Chargers |
| 2010-12-16 | 49ers Fall Flat in San Diego |
| 2010-12-17 | Los 49ers Caen Plenamente en San Diego |
| 2010-12-17 | Singletary's Notebook: Dec. 16 |
| 2010-12-20 | 49ers Hold Fan Appreciation Day |
| 2010-12-20 | Second Look: St. Louis Rams |
| 2010-12-21 | Singletary's Notebook: Dec. 21 |
| 2010-12-21 | 49ers Deliver Holiday Joy to Children |
| 2010-12-21 | Dixon’s Hype is for Real |
| 2010-12-22 | Third Down Success Defines 49ers |
| 2010-12-23 | Statement on Candlestick Park Agreement |
| 2010-12-23 | Singletary's Notebook: Dec. 23 |
| 2010-12-23 | From One Smith to Another |
| 2010-12-24 | Teams Talk: Adams on St. Louis |
| 2010-12-26 | Points of the Game: Rams |
| 2010-12-26 | Playoff Hopes Dashed in St. Louis |
| 2010-12-26 | 49ers Relieve Singletary of Coaching Duties |
| 2010-12-27 | Las Esperanzas de Postemporada se Desvanecen en St. Louis |
| 2010-12-27 | 49ers Foundation Grants $1.8 Million in 2010 |
| 2010-12-28 | Second Look: Arizona Cardinals |
| 2010-12-28 | Willis, Smith Return to the Pro Bowl |
| 2010-12-29 | 49ers Celebrate 2010 CARE Program |
| 2010-12-29 | 49ers Sign LB Joseph |
| 2010-12-29 | 49ers Announce Team Award Winners |
| 2010-12-29 | Coach's Notebook: Dec. 29 |
| 2010-12-30 | Justin Smith Wins Courage Award |
| 2010-12-30 | Sticking With the Starters |
| 2010-12-30 | 49ers Celebrate Bay Area Youth Football |
| 2010-12-31 | Teams Talk: Jennings on Arizona |
| 2010-12-31 | A Look Back at 2010 |
