| 2018-10-01 | 10 Takeaways: Chargers 29, 49ers 27 in Week 4 |
| 2018-10-01 | Matt Breida: 'C.J. Beathard Is Going to Be a Great Quarterback in This League' |
| 2018-10-01 | By the Numbers: George Kittle's Record-breaking Performance |
| 2018-10-01 | Kyle Shanahan Provides Comprehensive Post-Week 4 Injury Report |
| 2018-10-02 | 5 49ers Who Impressed in Week 4 According to Pro Football Focus |
| 2018-10-02 | 49ers name Pablo Villasenor 2018 Week 6 Player of the Week |
| 2018-10-02 | 49ers select Ryan Partridge of Liberty High School as the Charlie Wedemeyer Memorial Coach of the Week Presented by U.S. Bank |
| 2018-10-03 | George Kittle, Matt Breida Named to Pro Football Focus' First Quarter All-Pro Team |
| 2018-10-03 | Team Comparisons: 49ers Host First Divisional Matchup of 2018 against Cardinals |
| 2018-10-04 | The Prospector: 49ers vs. Cardinals in Week 5 |
| 2018-10-04 | Why George Kittle and C.J. Beathard Aren't the Only Former Hawkeyes You Should Be Watching |
| 2018-10-05 | Meet the 2018 Gold Rush Squad: Natalie and Alexa |
| 2018-10-05 | The Bourne Identity: Kendrick Could Be Called upon in Week 5 |
| 2018-10-05 | De Vuelta a Casa
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| 2018-10-05 | Marquise Goodwin Has a '50/50' Chance to Play in Week 5 |
| 2018-10-05 | Where to Watch: San Francisco 49ers vs. Arizona Cardinals |
| 2018-10-05 | Four Downs: Keys to a 49ers Win against the Cardinals |
| 2018-10-06 | 49ers Activate WR Victor Bolden Jr., Promote DL Ryan Delaire |
| 2018-10-07 | 49ers Announce Week 5 Inactives vs. Cardinals |
| 2018-10-07 | 6 Takeaways: Cardinals 28, 49ers 18 in Week 5 |
| 2018-10-08 | 49ers select Mike Holt as Coach of the Week Presented by U.S. Bank |
| 2018-10-08 | 6 49ers Who Impressed in Week 5 According to Pro Football Focus |
| 2018-10-09 | 49ers Week 7 Matchup vs. Rams Moved to 1:25 p.m. PT |
| 2018-10-09 | 49ers Announce Several Practice Squad Roster Moves |
| 2018-10-10 | 49ers Foundation and Jerry Rice Announce 1st and Bowl Challenge |
| 2018-10-10 | Team Comparison: 49ers To Visit Packers on Primetime |
| 2018-10-11 | The Story Behind Alfred Morris’ Trademark Home Run Hitting Touchdown Celebration |
| 2018-10-11 | Marquise Goodwin on Track to Give 49ers Offense a Primetime Boost |
| 2018-10-13 | Where to Watch: San Francisco 49ers at Green Bay Packers |
| 2018-10-15 | Four Downs: Which 49ers Player Must Step up in Primetime? |
| 2018-10-15 | Un Duelo de Lunes Por La Noche |
| 2018-10-15 | 49ers Promote TE Ross Dwelley, Waive DL Ryan Delaire |
| 2018-10-15 | Matt Breida, George Kittle Active for 'Monday Night Football' |
| 2018-10-16 | Highlight Rundown: 49ers at Packers (Week 6) |
| 2018-10-16 | 11 Takeaways: Packers 33, 49ers 30 in Week 6 |
| 2018-10-16 | 49ers Sign QB Tom Savage, Announce Other Roster Moves |
| 2018-10-16 | Joe Staley: ‘It's on Everybody, Not Just One Person’ |
| 2018-10-16 | 49ers Select Dominick Mazotti as 2018 Week 8 Player of the Week |
| 2018-10-17 | 6 49ers Who Impressed in Week 6 According to Pro Football Focus |
| 2018-10-17 | 49ers Open Practice Window for Rookie Safety Marcell Harris |
| 2018-10-18 | Team Comparisons: 49ers Host Undefeated Rams in Week 7 |
| 2018-10-19 | Statues and Ceremonies: 49ers Gearing up for a Star-studded Alumni Weekend |
| 2018-10-19 | What are the Rams Saying About the 49ers? |
| 2018-10-19 | Where to Watch: San Francisco 49ers vs. Los Angeles Rams
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| 2018-10-19 | Four Downs: Keys to a 49ers Upset Win over the Rams |
| 2018-10-20 | 49ers Promote DB Tyvis Powell, Waive QB Tom Savage |
| 2018-10-22 | 49ers Unveil High School Community Corner Presented by U.S. Bank |
| 2018-10-22 | 49ers Place DB Adrian Colbert on IR, Sign QB Tom Savage |
| 2018-10-23 | 49ers Sign WR Aaron Burbridge to the Practice Squad |
| 2018-10-23 | 49ers Aren’t Looking for a ‘Quick Fix’ Despite 1-6 Start to 2018 |
| 2018-10-23 | 49ers Select Jaremmy Kanongataa as Week 9 Player of the Week |
| 2018-10-23 | 49ers Select Bryan Smith as Wedemeyer Memorial Coach of the Week |
| 2018-10-24 | Team Comparison: 49ers Aim to Split Season Series against Cardinals |
| 2018-10-26 | George Kittle: The 49ers Star Tight End in the Making with a WWE-sized Persona |
| 2018-10-26 | Meet the 2018 Gold Rush Squad: Anelisse and Sierrah |
| 2018-10-26 | Where to Watch: San Francisco 49ers at Arizona Cardinals |
| 2018-10-26 | Los 49ers Visitan a Los Cardenales para Una Revancha |
| 2018-10-28 | Matt Breida, Richard Sherman Active against Cardinals in Week 8 |
| 2018-10-30 | 49ers Waive WR Victor Bolden Jr. and DB Greg Mabin |
| 2018-10-30 | 49ers select Fresh Ison of Moreau Catholic High School as the 2018 Week 10 Player of the Week Presented by U.S. Bank |
| 2018-10-30 | 49ers select Frank Lopez Jr. as Charlie Wedemeyer Memorial Coach of the Week |
| 2018-10-31 | Team Comparison: 49ers and Raiders Take to Primetime in the Final 'Battle of the Bay' |
| 2018-10-31 | Where to Watch: San Francisco 49ers vs. Oakland Raiders |
