| 2016-10-01 | 49ers Promote TE Je'Ron Hamm to Active Roster; Release RB DuJuan Harris |
| 2016-10-02 | Live Updates: San Francisco 49ers vs. Dallas Cowboys |
| 2016-10-02 | What We Learned: Cowboys 24 - 49ers 17 |
| 2016-10-03 | What the 49ers, Cowboys Said after Week 4 |
| 2016-10-03 | 6 Game Notes from 49ers Week 4 Loss to the Dallas Cowboys |
| 2016-10-03 | 49ers Snap Count: Week 4 vs. Dallas Cowboys |
| 2016-10-03 | 49ers LB NaVorro Bowman Out for the Season with Achilles Injury |
| 2016-10-03 | 49ers select Noah Cryns as the Week 5 Player of the Week |
| 2016-10-03 | Trevor Pruitt, Los Altos H.S., Awarded Week 5 Coach of the Week |
| 2016-10-03 | Aaron Lynch Set to Return to 49ers Defense on TNF vs. Arizona Cardinals |
| 2016-10-04 | 5 Wide Receiver Updates from 49ers OC Curtis Modkins |
| 2016-10-05 | How Will the 49ers Replace NaVorro Bowman? |
| 2016-10-05 | Semana 5 - Jueves de Color Rush |
| 2016-10-05 | 49ers CB Rashard Robinson Receives Praise from Coaches, Media after First NFL Start |
| 2016-10-05 | What's Happening at This Week's 49ers Game |
| 2016-10-05 | Where to Watch San Francisco 49ers vs. Arizona Cardinals |
| 2016-10-05 | Four Downs: Predictions for 49ers vs. Cardinals on TNF |
| 2016-10-06 | Antoine Bethea Takes Active Role in Fight against Breast Cancer |
| 2016-10-06 | 49ers Activate LB Aaron Lynch; Place LB NaVorro Bowman on Injured Reserve |
| 2016-10-06 | Live Updates: San Francisco 49ers vs. Arizona Cardinals |
| 2016-10-06 | What We Learned: Cardinals 33 - 49ers 21 |
| 2016-10-07 | 49ers Select Jai Austin as the Week 6 Player of the Week |
| 2016-10-07 | Matt Kiesle, Piedmont High School, Awarded Week 6 Coach of the Week |
| 2016-10-07 | 'A Football Life: Steve Young' Set to Premiere on NFL Network |
| 2016-10-07 | Faithful Rewards Announces Miami Road Trip Sweepstakes |
| 2016-10-10 | 49ers Sign CB Jacorey Shepherd, Place CB Chris Davis on Injured Reserve |
| 2016-10-10 | Meet the 2016 Gold Rush Squad: Cassie and Sophia |
| 2016-10-11 | 49ers RB Carlos Hyde among League Leaders |
| 2016-10-11 | 49ers Announce Colin Kaepernick Will Start vs. Buffalo Bills |
| 2016-10-11 | Hall of Fame QB Steve Young Releases New Book |
| 2016-10-11 | A Football Life: Steve Young |
| 2016-10-12 | 49ers Alumni Riki Ellison to be Inducted into Polynesian Football Hall of Fame |
| 2016-10-12 | 49ers Coordinators Preview Week 6 Road Matchup with Buffalo Bills |
| 2016-10-13 | 49ers Rookie G Joshua Garnett Gives Update on Personal Growth |
| 2016-10-13 | Phil Dawson's Greatest Hits |
| 2016-10-13 | 49ers STEAM Education Program Makes Impact at 2016 California STEM Symposium |
| 2016-10-14 | 49ers Expect Heavy Pressure from Rex Ryan-coached Buffalo Bills |
| 2016-10-14 | Four Downs: Predictions for Colin Kaepernick's First Start in 2016 |
| 2016-10-14 | Meet the 2016 Gold Rush Squad: Marissa and Yuri |
| 2016-10-14 | Faithful Since Tittle: Meet Jim Walker and Audrey Rose |
| 2016-10-14 | Where to Watch San Francisco 49ers at Buffalo Bills |
| 2016-10-14 | 49ers select Demarii Blanks of Carlmont High School as the Week 7 Player of the Week |
| 2016-10-14 | 49ers PREP Selects Carlo Maningo Week 7 Coach of the Week |
| 2016-10-16 | Live Updates: San Francisco 49ers at Buffalo Bills |
| 2016-10-16 | Colin Kaepernick Throws for 187 Yards, One Touchdown in 2016 Debut |
| 2016-10-17 | 49ers Snap Count: Week 6 at Buffalo Bills |
| 2016-10-18 | 49ers Sign WR DeAndre Smelter to Practice Squad, Release WR Dres Anderson |
| 2016-10-18 | Anatomy of a Play: Torrey Smith's 53-yard Touchdown Catch vs. Buffalo Bills |
| 2016-10-18 | 49ers Coordinators Give Updates on Colin Kaepernick, Rush Defense before Week 7 |
| 2016-10-18 | Colin Kaepernick Shares Expectations for Second Start of 2016 Season |
| 2016-10-19 | 49ers Attend Sport at the Service of Humanity Conference |
| 2016-10-19 | 49ers Rookie CB Will Redmond Returns to Practice |
| 2016-10-19 | Semana 7 - Tiempo de Volar |
| 2016-10-19 | Jimmie Ward: 49ers Must Make Bucs One Dimensional |
| 2016-10-20 | Get to Know 49ers CB Keith Reaser |
| 2016-10-20 | How to Enter into Miami Road Trip Sweepstakes |
| 2016-10-20 | What's Happening at This Week's 49ers Game |
| 2016-10-21 | Chris Oswald, Cupertino High School, Awarded Week 8 Coach of the Week |
| 2016-10-21 | Notebook: Carlos Hyde Ruled Out for Week 7 vs. Tampa Bay |
| 2016-10-21 | Four Downs: Bold Predictions for 49ers-Bucs Game |
| 2016-10-21 | Where to Watch San Francisco 49ers vs. Tampa Bay Buccaneers |
| 2016-10-21 | Meet the 2016 Gold Rush Squad: Shasta and Montana |
| 2016-10-22 | 49ers Promote RB DuJuan Harris to Active Roster, Waive DT Taylor Hart |
| 2016-10-23 | Live Updates: San Francisco 49ers vs. Tampa Bay Buccaneers |
| 2016-10-23 | What We Learned: Buccaneers 34 - 49ers 17 |
| 2016-10-24 | Colin Kaepernick: We Have to Overcome Adversity |
| 2016-10-24 | 49ers Snap Count: Week 7 vs. Tampa Bay Buccaneers |
| 2016-10-25 | Meet the 2016 Gold Rush Squad: Kayla and Taylor |
| 2016-10-25 | 49ers select Lucas Flygare as the Week 8 Player of the Week |
| 2016-10-29 | Milo Lewis, Homestead High School, Awarded Week 9 Coach of the Week |
| 2016-10-29 | 49ers Select Chris Denning as Week 9 Player of the Week |
| 2016-10-31 | What the 49ers Did During the Bye Week |
| 2016-10-31 | Coach K: Daniel Kilgore Shares Bond With Special Needs Community |
