Follow along with 49ers.com for in-game updates, highlights, stats and analysis during the team's Week 18 matchup at Levi's® Stadium.
- Arizona Cardinals vs. San Francisco 49ers
- Sunday, January 8, 2022
- Levi's® Stadium
About the Matchup
- Total Matchups: 62
- Series Record: 49ers lead the series 33-29
- 49ers Home Record vs. Arizona: 49ers lead the series 18-14