| 2019-09-01 | Position-by-position Break Down of the 49ers Initial 53-man Roster |
| 2019-09-01 | 49ers Sign 9 Players to Practice Squad |
| 2019-09-01 | Análisis de la Plantilla Final de 53 Hombres de los 49ers |
| 2019-09-01 | 49ers Place DL Kentavius Street on IR, Sign DB Antone Exum |
| 2019-09-02 | 49ers Sign OL Ryan Pope to Practice Squad |
| 2019-09-02 | Inicia la Temporada 2019 Para 49ers en Tampa Bay |
| 2019-09-04 | 49ers Introduce Zenni Optical as Official Eyewear Partner |
| 2019-09-05 | In My Own Words: This Time, it Counts |
| 2019-09-05 | 49ers Announce Single-game Ticket On-sale and Fan Giveaways for 2019 Regular Season |
| 2019-09-05 | 5 Key Matchups: 49ers Season Opener vs. Buccaneers |
| 2019-09-06 | 49ers PREP selects Brad Bowers as Coach of the Week |
| 2019-09-06 | 49ers vs. Buccaneers: Where to Watch & Game Preview |
| 2019-09-06 | 49ers PREP select Caleb Ojeda as the 2019 Week 1 Player of the Week |
| 2019-09-06 | Kyle Shanahan Provides Injury Update Ahead of Opener in Tampa |
| 2019-09-06 | Four Downs: Previewing 49ers and Buccaneers 'Heated' Week 1 Contest |
| 2019-09-08 | Nick Bosa to Play in 49ers Season Opener vs. Buccaneers |
| 2019-09-09 | 49ers Arrancan la Temporada con una Victoria de Visitantes |
| 2019-09-09 | 14 Takeaways from 49ers 31-17 Week 1 Victory Over the Buccaneers |
| 2019-09-09 | What They Said: 49ers and Buccaneers Reactions to Week 1 |
| 2019-09-09 | Kyle Shanahan Offers Injury Updates on Tevin Coleman and More Following 49ers Week 1 Victory |
| 2019-09-10 | Stats and Facts: 49ers Defense makes Dominant Debut against Buccaneers |
| 2019-09-10 | 5 49ers Who Impressed in the Week 1 Victory over the Buccaneers |
| 2019-09-10 | 49ers Viajan a Cincinnati Buscando su Segunda Victoria |
| 2019-09-12 | 49ers vs. Bengals: Where to Watch & Game Preview |
| 2019-09-12 | 5 Key Matchups: 49ers vs. Bengals |
| 2019-09-13 | Patrick Willis, John Lynch Announced as Nominees for Hall of Fame Class of 2020 |
| 2019-09-13 | 49ers PREP select Joe Bates as Wedemeyer Memorial Coach of the Week |
| 2019-09-13 | 49ers PREP selects Matt Meredith of Miramonte High School as the 2019 Week 2 Player of the Week presented by U.S. Bank |
| 2019-09-13 | Nick Bosa Questionable Ahead of Week 2 Matchup against Bengals |
| 2019-09-13 | Four Downs: Reasonable Expectations for Jimmy Garoppolo vs. Bengals |
| 2019-09-14 | 49ers Promote RB Jeff Wilson; Waive TE Kaden Smith |
| 2019-09-15 | Nick Bosa, Joe Mixon Expected to Play in Week 2 |
| 2019-09-15 | 16 Takeaways as 49ers Tame Bengals in 41-17 Victory |
| 2019-09-16 | 49ers Vencen a Bengals en una Contundente Victoria. |
| 2019-09-16 | What They Said: 49ers and Bengals Reactions to Week 2 |
| 2019-09-16 | 49ers Offense Sees Significant Production In Week 2 vs. Bengals |
| 2019-09-16 | 6 49ers Who Impressed in 41-17 Victory Over the Bengals |
| 2019-09-17 | Jimmy G, Deebo Samuel Earn 'Player of the Week' Nominations |
| 2019-09-17 | John Taylor Announces He will Join Players and Fans on the Faithful Cruise in February! 🙌 |
| 2019-09-17 | 49ers Announce Roster Moves |
| 2019-09-18 | 49ers Reciben a Steelers Para Su Primer Partido en Casa |
| 2019-09-19 | 49ers Partner With Gold Bar® Whiskey as Official Whiskey of the 49ers |
| 2019-09-19 | 49ers vs. Steelers: Where to Watch & Game Preview |
| 2019-09-19 | 49ers Announce Cache Creek Casino Resort, Yocha Dehe Wintun Nation Partnership |
| 2019-09-20 | 49ers to Build an 8K Ecosystem with Foxconn Industrial Internet |
| 2019-09-20 | 5 Key Matchups: 49ers Home Opener vs. Steelers |
| 2019-09-20 | 49ers Sign T Sam Young; Place WR Trent Taylor on Injured Reserve |
| 2019-09-20 | The 49ers Foundation 50/50 Raffle on Track to Hit the $1 Million Mark |
| 2019-09-20 | Kyle Shanahan Addresses Trent Taylor to IR, Dee Ford Questionable in Week 3 |
| 2019-09-21 | 49ers Have Eight of the Top 100 Plays in NFL History |
| 2019-09-21 | Four Downs: Who to Watch for in 49ers Home Opener vs. Steelers |
| 2019-09-22 | Jason Verrett to Make his 49ers Debut vs. Steelers |
| 2019-09-22 | 49ers Vencen a Steelers a Pesar de Todo |
| 2019-09-23 | 10 Takeaways: Entering Bye Week 3-0 |
| 2019-09-23 | What They Said: 49ers, Steelers React to Intense Battle in Week 3 |
| 2019-09-23 | Stats and Facts: 49ers Turn Steel into Gold in Victory Over Pittsburgh |
| 2019-09-23 | Tevin Coleman, Jalen Hurd to Return After Bye, Ahkello Witherspoon to Miss Time |
| 2019-09-24 | 49ers Bringing Award-winning STEAM Education Program to Fiji |
| 2019-09-24 | 7 Top Performers from 49ers Week 3 Victory Over Steelers |
| 2019-09-24 | 49ers Sign LS Garrison Sanborn |
| 2019-09-25 | San Francisco 49ers and Peet's Coffee Announce Multi-year Partnership |
| 2019-09-25 | What They're Saying About the 49ers - Week 4 Power Rankings 📈 |
| 2019-09-26 | Getting Reacquainted with Safety Jaquiski Tartt |
| 2019-09-27 | 49ers PREP names Nick Morris 2019 Week 3 Player of the Week |
| 2019-09-27 | 49ers PREP Selects Floyd Burnsed as Coach of the Week |
| 2019-09-29 | 49ers PREP selects Jerry Johnson of Pittsburg High School as the 2019 Week 4 Player of the Week presented by U.S. Bank |
| 2019-09-29 | 49ers PREP selects Kevin Macy of Campolindo High School as Coach of the Week |
| 2019-09-30 | 49ers Reciben a Browns Para el Primer Partido del Año en Horario Estelar |
