Follow along with 49ers.com for in-game updates, highlights, stats and analysis during the team's Week 16 matchup against the Tennessee Titans at Nissan Stadium.
- San Francisco 49ers vs. Tennessee Titans
- Thursday, December 23, 2021
- Nissan Stadium
OTHER GAME INFO
Check out some of the top photos as the 49ers fly to Tennessee to face the Titans, presented by United.