San Francisco 49ers Injury Report

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Christian McCaffrey Active for Season Opener; Inactives for #SFvsSEA

Take a look at players who have been ruled out for the San Francisco 49ers Week 1 matchup versus the Seattle Seahawks.

Christian McCaffrey Questionable for Week 1; Injury Report Ahead of #SFvsSEA

The San Francisco 49ers released their latest injury updates headed into the 2025 season opener versus the Seattle Seahawks.

George Kittle, Colton McKivitz Active vs. Cardinals; Inactives for #SFvsAZ

San Francisco 49ers tight end George Kittle and offensive lineman Colton McKivitz are active for the team's 2024 season finale versus the Arizona Cardinals.

TE George Kittle Questionable, WR Deebo Samuel Sr. OUT for #SFvsAZ

The San Francisco 49ers released their latest injury updates headed into the 2024 season finale versus the Arizona Cardinals.

OL Colton McKivitz and S Ji'Ayir Brown Active for Week 17 vs. Lions; Inactives for #DETvsSF

San Francisco 49ers safety Ji'Ayir Brown and right tackle Colton McKivitz are active for the team's Week 17 matchup versus the Detroit Lions.

Spencer Burford OUT, Colton McKivitz Questionable for #DETvsSF

The San Francisco 49ers released their latest injury updates headed into the team's Week 17 matchup vs. the Detroit Lions.

Nick Bosa and Dre Greenlaw Active Week 16 vs. Dolphins; Inactives for #SFvsMIA

San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are active for the team's Week 16 matchup vs. the Miami Dolphins after entering the weekend as questionable.

Nick Bosa and Dre Greenlaw Questionable for Week 16; Injury Report Ahead of #SFvsMIA

The San Francisco 49ers released their latest injury updates headed into the team's Week 16 matchup vs. the Miami Dolphins.

Dre Greenlaw and Nick Bosa Active vs. Rams; Inactives for #LARvsSF

San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are set to make their return from injury versus the Los Angeles Rams on "Thursday Night Football."

Isaac Guerendo and Nick Bosa Questionable for Week 15; Injury Report Ahead of #LARvsSF

The San Francisco 49ers released their latest injury updates headed into the team's Week 15 "Thursday Night Football" matchup vs. the Los Angeles Rams.

Hufanga, Lenoir and Elliott Set to Return vs. Bears; Inactives for #CHIvsSF

San Francisco 49ers safety Talanoa Hufanga, defensive back Deommodore Lenoir and defensive lineman Jordan Elliott are set to make their return from injury versus the Chicago Bears.

Trent Williams Out, Nick Bosa Doubtful and Aaron Banks Questionable for #CHIvsSF

The San Francisco 49ers released their latest injury updates headed into the team's Week 14 matchup vs. the Chicago Bears.

Brock Purdy Active vs. Bills; Inactives for #SFvsBUF

San Francisco 49ers quarterback Brock Purdy is active for the team's Week 13 matchup versus the Buffalo Bills.

Brock Purdy Questionable, Trent Williams Out for Week 13 vs. Bills; Injury Report #SFvsBUF

The San Francisco 49ers released their latest injury updates headed into the team's Week 13 matchup vs. the Buffalo Bills.

Trent Williams and Brock Purdy OUT vs. Packers; Inactives for #SFvsGB

San Francisco 49ers left tackle Trent Williams has been sidelined for the team's Week 12 matchup vs. the Green Bay Packers.

Brock Purdy, Nick Bosa Ruled Out for Week 12 vs. Packers; Injury Report #SFvsGB

The San Francisco 49ers released their latest injury updates headed into the team's Week 12 matchup vs. the Green Bay Packers.

Kittle OUT, Williams and Bosa Active vs. Seahawks; Inactives for #SEAvsSF

San Francisco 49ers tight end George Kittle was sidelined for the team's Week 11 matchup vs. the Seattle Seahawks.

Kittle, Bosa and Williams Questionable for Week 11 vs. Seahawks; Injury Report #SEAvsSF

The San Francisco 49ers released their latest injury updates headed into the team's Week 11 matchup vs. the Seattle Seahawks.

Christian McCaffrey and Nick Bosa Active vs. Buccaneers; Inactives for #SFvsTB

San Francisco 49ers running back Christian McCaffrey is active for the team's Week 10 matchup vs. the Tampa Bay Buccaneers.

Christian McCaffrey, Nick Bosa Questionable for Week 10 vs. Buccaneers; Injury Report #SFvsTB

The San Francisco 49ers released their latest injury updates headed into the team's Week 10 matchup vs. the Tampa Bay Buccaneers.

San Francisco 49ers

Table - Injury report
Player	Position	Injury	Wed	Game Status
Ben Bartch	OL	Knee, Elbow	LP	UNSPECIFIED
Nick Bosa	DL	Resting Player	DNP	UNSPECIFIED
Luke Gifford	LB	Knee	FP	UNSPECIFIED
Yetur Gross-Matos	DL	Knee	DNP	UNSPECIFIED
Jordan James	RB	Finger	LP	UNSPECIFIED
Mac Jones	QB	Knee	FP	UNSPECIFIED
Jauan Jennings	WR	Shoulder	DNP	UNSPECIFIED
Christian McCaffrey	RB	Calf, Resting Player	DNP	UNSPECIFIED
Dominick Puni	OL	Knee	FP	UNSPECIFIED
Brock Purdy	QB	Left Shoulder, Toe	DNP	UNSPECIFIED
Jordan Watkins	WR	Ankle	LP	UNSPECIFIED
Trent Williams	T	Knee, Rest	DNP	UNSPECIFIED

New Orleans Saints

Table - Injury report
Player	Position	Injury	Wed	Game Status
Julian Blackmon	SAF	Shoulder	DNP	UNSPECIFIED
Taliese Fuaga	OT	Knee	DNP	UNSPECIFIED
Trevor Penning	OT	Toe	DNP	UNSPECIFIED
Chase Young	DE	Calf	DNP	UNSPECIFIED
Velus Jones Jr.	RB	Knee	LP	UNSPECIFIED
Zach Wood	LS	Elbow	LP	UNSPECIFIED
Jordan Howden	SAF	Oblique	FP	UNSPECIFIED

Legend

Practice Status
- DNP - Did not participate in practice
- LP - Limited participation in practice
- FP - Full participation
- (-) - Not listed

Game Status
- Out - Player will not play
- Doubtful - Player is unlikely to play
- Questionable - Player is not certain to play
- (-) - Not listed

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