The 49ers have signed RB Trey Sermon to a four-year deal and claimed WR Nsimba Webster off waivers from the Los Angeles Rams.

The 49ers have waived LB Nathan Gerry.

The 49ers have signed OL Senio Kelemete to a one-year deal and waived/injured OL Justin Skule.

The 49ers have signed S Tony Jefferson to a one-year deal and released CB Briean Boddy-Calhoun.

The 49ers have signed TE MyCole Pruitt to a one-year deal.

The 49ers announced that center Weston Richburg has retired from the National Football League.

The 49ers have signed LB James Burgess Jr. to a one-year deal.

The 49ers have signed WR Andy Jones to a one-year deal. The team has also waived TE Daniel Helm and released QB Josh Johnson.

The 49ers have signed WR Bennie Fowler to a one-year deal and waived WR Marqise Lee.

The 49ers have signed WR Marqise Lee to a one-year deal and waived WR Austin Proehl.

The 49ers have signed undrafted rookie free agents OL Alfredo Gutierrez, LB Justin Hilliard, TE Josh Pederson, LB Elijah Sullivan and WR Austin Watkins Jr..

The 49ers have signed OL Aaron Banks, OL Jaylon Moore, DB Deommodore Lenoir, S Talanoa Hufanga and RB Elijah Mitchell to four-year deals.

The 49ers have waived RB Austin Walter.

The 49ers have waived CB Adonis Alexander, WR Matt Cole and S Chris Edwards.

With the 194th overall pick in the 2021 NFL Draft, the 49ers select Elijah Mitchell.

With the 180th overall pick in the 2021 NFL Draft, the 49ers select Talanoa Hufanga.

With the 172nd overall pick in the 2021 NFL Draft, the 49ers select Deommodore Lenoir.

With the 155th overall pick in the 2021 NFL Draft, the 49ers select Jaylon Moore.

With the 102nd overall pick in the 2021 NFL Draft, the 49ers select Ambry Thomas.

With the 88th overall pick in the 2021 NFL Draft, the 49ers select Trey Sermon.

With the 48th overall pick in the 2021 NFL Draft, the 49ers select Aaron Banks.

The 49ers have waived DB Obi Melifonwu who signed a Reserve/Future contract with San Francisco on January 4, 2021.

With the 3rd overall pick in the 2021 NFL Draft, the 49ers select Trey Lance.

The 49ers have re-signed OL Tom Compton to a one-year deal.

The 49ers have waived DL Josiah Coatney who signed a Reserve/Future contract with San Francisco on January 4, 2021.

The 49ers have signed DL Maurice Hurst and DL Arden Key to one-year deals.

The 49ers have signed RB Wayne Gallman Jr. to a one-year deal.

The 49ers have waived TE Chase Harrell.

The 49ers announce that exclusive rights free agent OL Daniel Brunskill has signed his one-year tender.

The 49ers have signed quarterback Nate Sudfeld to a one-year deal.

The 49ers announced on Thursday they have re-signed CB Jason Verrett to a one-year deal.

The 49ers have signed WR Mohamed Sanu to a one-year deal.

The 49ers have signed LB Nathan Gerry (GARY) to a one-year deal.

The 49ers have re-signed CB K'Waun Williams to a one-year deal.

The 49ers have re-signed DL Jordan Willis to a one-year deal.

The 49ers have re-signed All-Pro T Trent Williams to a six-year deal through the 2026 season.

The 49ers have signed DL Zach Kerr to a one-year deal.

The 49ers have re-signed defensive lineman D.J. Jones to a one-year deal.

The 49ers have re-signed S Jaquiski Tartt to a one-year deal.

The 49ers have signed safety Tavon Wilson to a one-year deal.

The 49ers have re-signed CB Dontae Johnson to a one-year deal.

The 49ers have signed WR Trent Sherfield to a one-year deal.

The 49ers have signed DL Samson Ebukam to a two-year deal.

The 49ers have re-signed CB Briean (BREE-in) Boddy-Calhoun and TE Daniel Helm to one-year deals.

The 49ers have signed CB Emmanuel Moseley to a two-year extension through the 2022 season.

The 49ers have signed Pro Bowl FB Kyle Juszczyk to a five-year extension through the 2025 season.

The 49ers have tendered a one-year contract to exclusive rights free agent OL Daniel Brunskill and released DL Ronald Blair III.

The 49ers have signed TE Ross Dwelley and S Marcell Harris to one-year extensions. Additionally, the team declined the 2021 contract option for LB Mark Nzeocha.

The 49ers have claimed CB Mark Fields II off waivers from the Houston Texans.

The 49ers have signed WR River Cracraft to a one-year extension.

The 49ers have signed LS Taybor Pepper to a two-year contract extension through the 2022 season.

The 49ers have re-signed restricted free agent RB Jeff Wilson Jr. to a one-year deal.

The 49ers have re-signed exclusive rights free agent CB Ken Webster to a one-year deal.

The 49ers have signed QB Josh Johnson and OL Corbin Kaufusi to a Reserve/Future contract.

The 49ers have waived LS Colin Holba. The 49ers have signed TE Chase Harrell and S Jared Mayden to reserve/futures contracts.

The 49ers have waived P Drew Kaser and signed the following 13 free agents to Reserve/Future contracts CB Adonis Alexander, DL Josiah Coatney, S Chris Edwards, LB Jonas Griffith, DL Daeshon Hall, CB Tim Harris Jr., FB Josh Hokit, WR Jauan Jennings, DB Obi Melifonwu, WR Austin Proehl, OL Dakoda Shepley, WR Kevin White and OL Isaiah Williams.

The 49ers have signed P Drew Kaser to the team's practice squad. OL Tom Compton has been activated from the Injured Reserve List. DL Josiah Coatney and OL Isaiah Williams have been activated from the team's practice squad (COVID-19 replacement). WR Jordan Matthews and K Tristan Vizcaino have been activated from the team's practice squad (standard elevation). OL Aaron Neary has been released from the team's practice squad.