| 2012-09-01 | 49ers Sign Eight to the Practice Squad |
| 2012-09-01 | Coach's Notebook: Sept. 1 |
| 2012-09-03 | 49ers Sign LB Haggans, LB Haralson to IR |
| 2012-09-05 | Whitner’s Blog: Season Begins |
| 2012-09-05 | 49ers Prepped for Passing Packers |
| 2012-09-06 | 49ers to Host Red and Gold Rally |
| 2012-09-06 | Coordinators Discuss Green Bay Matchup |
| 2012-09-07 | Looney's Blog: Ready for Green Bay |
| 2012-09-07 | Coach's Notebook: Sept. 7 |
| 2012-09-11 | FCFS Named Week 1 HS Players of the Week |
| 2012-09-11 | 49ers Pack Extra Punch on O-line |
| 2012-09-11 | Vernon Davis Improves Ball Skills |
| 2012-09-12 | 49ers Sign 12-Year Extension with Cumulus |
| 2012-09-12 | Coach's Notebook: Sept. 12 |
| 2012-09-13 | Frank Gore’s Style, All His Own |
| 2012-09-13 | 49ers Expect Physical Matchup |
| 2012-09-15 | Tavares Gooden: Showstopper |
| 2012-09-16 | Vernon Davis Scores Twice in Win |
| 2012-09-18 | Awuzie Named Week 2 HS Player of the Week |
| 2012-09-18 | Borello Named Week 2 HS Coach of the Week |
| 2012-09-19 | Rookies Help First and Goal Program |
| 2012-09-19 | Coach's Notebook: Sept. 19 |
| 2012-09-19 | Alex Smith Stays Tough |
| 2012-09-21 | Coach's Notebook: Sept. 21 |
| 2012-09-21 | Whitner's Blog: On the Road Again |
| 2012-09-23 | Live Blog: 49ers at Vikings |
| 2012-09-24 | 49ers Announce SAP as Stadium Partner |
| 2012-09-24 | Coach's Notebook: Sept. 24 |
| 2012-09-25 | 49ers Impact Ohio Community |
| 2012-09-25 | Cantrell Named Week 3 HS Player of the Week |
| 2012-09-25 | Papin Named Week 3 HS Coach of the Week |
| 2012-09-26 | Mario Manningham Happy to Be Home |
| 2012-09-27 | Willis Preps for Tebow, Jets Run Game |
| 2012-09-27 | Coordinators Gear Up for Familiar Foes |
| 2012-09-28 | Coach's Notebook: Sept. 28 |
| 2012-09-30 | Live Blog: 49ers at Jets |
