History: 49ers at Rams
- The 49ers have won three of their four matchups at the Rams since their return to Los Angeles in 2016.
- San Francisco makes their debut in Los Angeles' SoFi Stadium, which opens in 2020.
Players and Coaches to Know:
49ers
- Head Coach: Kyle Shanahan
- Quarterback: Jimmy Garoppolo
- Wide Receiver: Deebo Samuel
- Defensive Lineman: Dee Ford
Rams
- Head Coach: Sean McVay
- Quarterback: Jared Goff
- Wide Receiver: Robert Woods
- Defensive Lineman: Aaron Donald
