The San Francisco 49ers 2010 regular season schedule is highlighted by four primetime games and a trip to London. With the most primetime games slated for San Francisco since 2002, the 49ers look to improve an overall primetime record of 58-29. This season also marks the first time in franchise history that the 49ers open the regular season with two consecutive primetime contests. In Week 8, the 49ers will square off against the Denver Broncos in London, England, marking the franchise's second international regular season game (at Arizona in Mexico City, 2005).
"This time of year is exciting for the fans as well as the players and coaches," said head coach Mike Singletary. "I am excited that our fans will have an opportunity to see us play some pretty good competition at home on a big stage early in the year. I am very excited that the country gets to see our players and how the 49ers play football. We feel very good about having four opportunities to play in prime time, and I think our players have earned the right to be seen. This is a big year for us in many ways. We need to continue to prepare and focus on the things we can control."
The 49ers begin the year on the road against the Seattle Seahawks on Sunday, September 12, marking the first time the two teams will have faced one another to open the season. San Francisco holds a 34-29-1 overall record in season openers, which includes a 6-3 record in their past nine opening contests.
The following week, on September 20, the 49ers will play their home opener on a national stage as they host the defending Super Bowl Champion New Orleans Saints on Monday Night Football. San Francisco holds a 39-24 overall record when playing on Monday night, which includes a 22-10 record at home. The 49ers will then take to the road for their next two games, squaring off against the Kansas City Chiefs for the first time since 2006, before traveling to Atlanta in hopes of avenging a home loss to the Falcons in 2009.
San Francisco returns home to Candlestick Park on October 10 to face the Philadelphia Eagles in front of a national television audience on Sunday Night Football. The matchup marks the first time the 49ers will be featured on NBC's Football Night in America. The 49ers have an overall record of 11-8 when playing on Sunday night, including an 8-4 record at home. The last time the 49ers played a nationally televised Sunday night contest was in 2005, when they squared off with the Arizona Cardinals in Mexico City.
The 49ers will play host to their cross-bay rival Oakland Raiders on October 17, marking the first time the two teams have played one another since a 34-20 49ers victory at Candlestick Park, in 2006. San Francisco has won three of the last four games in the series.
The 49ers begin their long trek East when they match up against the Carolina Panthers on October 24. San Francisco maintains a 4-4 record in away games against Carolina, who was a former NFC West foe of the 49ers from 1995 to 2001. San Francisco will then cross the Atlantic to London to face off against the Denver Broncos at Wembley Stadium. It marks the team's 10th time playing on an international stage, but just their second regular season game and first as the home team.
The 49ers return home from their trip across the pond to host the St. Louis Rams on November 14 in the first of five NFC West division games during the second half of the season. The following week, San Francisco concludes its NFC South slate as Tampa Bay visits on November 21.
San Francisco travels to Arizona the next week for its second Monday Night Football appearance of the season. The game will mark the fourth-straight season in which the 49ers and the Cardinals will have met on Monday night, with San Francisco holding a 2-1 record in those contests. San Francisco then travels to Lambeau Field for the second time in as many years to face the Packers, before returning home to host the Seattle Seahawks on December 12.
In Week 15, the 49ers make their way south to San Diego to square off against the Chargers in a nationally televised Thursday Night Football game on the NFL Network. It marks the 49ers second consecutive season playing on Thursday Night Football. San Francisco looks to improve upon a perfect 5-0 record when playing on a Thursday night.
The 49ers conclude the season with two division opponents. San Francisco will first travel to St. Louis to face the Rams before returning home for the season finale against Arizona.
*Please be aware that as part of the National Football League's agreement with NBC to televise Sunday Night Football, the NFL has implemented a flexible schedule for Sunday start times for the final eight weeks of the season.
This will allow the NFL to bring more attractive match-ups to a national audience late in the season. If any of the 49ers games are moved from the original start time, fans will be notified 12 days prior to the date of the game with the exception of a Week 17 game, where the notification will be six days to ensure a Sunday Night game with playoff implications. Starting time changes will be publicized on 49ers.com and through the local print, electronic and internet media.