Jimmy Garoppolo Out vs. Miami Dolphins with a Foot Injury

The San Francisco 49ers fell 12-6 to the Los Angeles Rams on "Thursday Night Football."

The San Francisco 49ers will celebrate their initiatives to promote social justice throughout the Bay Area in their Week 15 contest against the Los Angeles Rams. Take a look at the impact the team has made so far this season.

San Francisco 49ers defensive lineman Yetur Gross-Matos earned the NFC Defensive Player of the Week following a three-sack performance versus the Chicago Bears in Week 14. 

San Francisco 49ers head coach Kyle Shanahan detailed the urgency with which the team is playing headed into the final stretch of the regular season.

San Francisco 49ers running back Isaac Guerendo was nominated for the Pepsi Zero Sugar Rookie of the Week Award for Week 14 after scoring two touchdowns in his first-career start.

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 14 matchup versus the Chicago Bears.

San Francisco 49ers tight end George Kittle was nominated for the FedEx Air & Ground Player of Week 14 Award after racking up six catches for 151 yards against the Chicago Bears.

The San Francisco 49ers defeated the Chicago Bears 38-13 at Levi's® Stadium in Week 14.

San Francisco 49ers long snapper Taybor Pepper discussed his special ties to Ele's Place, his organization of choice for the NFL's My Cause My Cleats initiative.

San Francisco 49ers DB Deommodore Lenoir is showcasing his support for athletes with Down syndrome through custom-designed cleats honoring his little sister, Caleya, and Charvarius Ward's late daughter, Amani.

San Francisco 49ers running back Isaac Guerendo discussed being the "next man up" with Christian McCaffrey and Jordan Mason expected to miss significant time due to injury.

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup versus the Buffalo Bills.