The Trail is Set for the 49ers 2025 Season
Join Sourdough Sam and Clementine as he heads down the Golden Trail to tackle the 49ers 2025 regular season matchups.
(Week 1) San Francisco 49ers at Seattle Seahawks - September 7th, 2025
(Week 2) San Francisco 49ers at New Orleans Saints - September 14th, 2025
(Week 3) Arizona Cardinals at San Francisco 49ers - September 21st, 2025
(Week 4) Jacksonville Jaguars at San Francisco 49ers - September 28th, 2025
(Week 5) San Francisco 49ers at Los Angeles Rams - October 2nd, 2025
(Week 6) San Francisco 49ers at Tampa Bay Buccaneers - October 12th, 2025
(Week 7) Atlanta Falcons at San Francisco 49ers - October 19th, 2025
(Week 8) San Francisco 49ers at Houston Texans - October 26th, 2025
(Week 9) San Francisco 49ers at New York Giants - November 2nd, 2025
(Week 10) Los Angeles Rams at San Francisco 49ers - November 9th, 2025
(Week 11) San Francisco 49ers at Arizona Cardinals - November 16th, 2025
(Week 12) Carolina Panthers at San Francisco 49ers - November 24th, 2025
(Week 13) San Francisco 49ers at Cleveland Browns - November 30th, 2025
(Week 14) Bye Week
(Week 15) Tennessee Titans at San Francisco 49ers - December 14th, 2025
(Week 16) San Francisco 49ers at Indianapolis Colts - December 22nd, 2025
(Week 17) Chicago Bears at San Francisco 49ers - December 28th, 2025
(Week 18) Seattle Seahawks at San Francisco 49ers - TBD
