San Francisco 49ers 2025 Schedule in Photos
Check out the 49ers home and away matchups for the 2025 regular season.
(Week 1) San Francisco 49ers at Seattle Seahawks - September 7th, 2025
(Week 2) San Francisco 49ers at New Orleans Saints - September 14th, 2025
(Week 3) Arizona Cardinals at San Francisco 49ers - September 21st, 2025
(Week 4) Jacksonville Jaguars at San Francisco 49ers - September 28th, 2025
(Week 5) San Francisco 49ers at Los Angeles Rams - October 2nd, 2025
(Week 6) San Francisco 49ers at Tampa Bay Buccaneers - October 12th, 2025
(Week 7) Atlanta Falcons at San Francisco 49ers - October 19th, 2025
(Week 8) San Francisco 49ers at Houston Texans - October 26th, 2025
(Week 9) San Francisco 49ers at New York Giants - November 2nd, 2025
(Week 10) Los Angeles Rams at San Francisco 49ers - November 9th, 2025
(Week 11) San Francisco 49ers at Arizona Cardinals - November 16th, 2025
(Week 12) Carolina Panthers at San Francisco 49ers - November 24th, 2025
(Week 13) San Francisco 49ers at Cleveland Browns - November 30th, 2025
(Week 15) Tennessee Titans at San Francisco 49ers - December 14th, 2025
(Week 16) San Francisco 49ers at Indianapolis Colts - December 22nd, 2025
(Week 17) Chicago Bears at San Francisco 49ers - December 28th, 2025
(Week 18) Seattle Seahawks at San Francisco 49ers - TBD
