49ers 2021 Schedule in Photos
Take a look at the opponents the 49ers are set to face during the 2021 season.
2021 49ers Schedule
San Francisco 49ers vs Kansas City Chiefs
Preseason Week 1 TBD
2021 49ers Schedule
San Francisco 49ers at Los Angeles Chargers
Preseason Week 2 TBD
2021 49ers Schedule
San Francisco 49ers vs Las Vegas Raiders
Preseason Week 3 TBD
2021 49ers Schedule
San Francisco 49ers at Detroit Lions
Week 1 September 12 @ 10:00am
2021 49ers Schedule
San Francisco 49ers at Philadelphia Eagles
Week 2 September 19 @10:00am
2021 49ers Schedule
San Francisco 49ers vs Green Bay Packers
Week 3 September 26 @ 5:20pm
Sunday Night Football
2021 49ers Schedule
San Francisco 49ers vs Seattle Seahawks
Week 4 October 3 @ 1:05pm
2021 49ers Schedule
San Francisco 49ers at Arizona Cardinals
Week 5 October 10 @1:25pm
2021 49ers Schedule
San Francisco 49ers vs Indianapolis Colts
Week 7 October 24 @ 5:20pm
Sunday Night Football
2021 49ers Schedule
San Francisco 49ers at Chicago Bears
Week 8 October 31 @ 10:00am
2021 49ers Schedule
San Francisco 49ers vs Arizona Cardinals
Week 9 November 7 @ 1:25pm
2021 49ers Schedule
San Francisco 49ers vs Los Angeles Rams
Week 10 November 15 @ 5:15pm
Monday Night Football
2021 49ers Schedule
San Francisco 49ers at Jacksonville Jaguars
Week 11 November 21 @ 10:00 am
2021 49ers Schedule
San Francisco 49ers vs Minnesota Vikings
Week 12 November 28 @1:25pm
2021 49ers Schedule
San Francisco 49ers at Seattle Seahawks
Week 13 December 5 @ 5:20pm
Sunday Night Football
2021 49ers Schedule
San Francisco 49ers at Cincinnati Bengals
Week 14 December 12 @10:00am
2021 49ers Schedule
San Francisco 49ers vs Atlanta Falcons
Week 15 December 19 @1:05pm
2021 49ers Schedule
San Francisco 49ers at Tennessee Titans
Week 16 December 23 @ 5:20pm
Thursday Night Football
2021 49ers Schedule
San Francisco 49ers vs Houston Texans
Week 17 January 2 @ 1:05pm
2021 49ers Schedule
San Francisco 49ers at Los Angeles Rams
Week 18 January 9 @1:25pm
