Carlos Hyde, Four Others Questionable vs. Cardinals

The San Francisco 49ers Thursday night game couldn't have come at a more opportune time. The ten-day gap between Week 3 and 4 benefited the 49ers as they recovered from a handful of injuries suffered against the Los Angeles Rams.

One of those players is running back Pierre Garçon.

After leaving the game briefly with a hip injury, Hyde returned against the Rams and ran for 84 yards and two touchdowns.

Hyde has been listed as questionable for Sunday after being limited in practice all week. On Friday, Hyde was more active than the previous days, however he is "still hurting" according to Kyle Shanahan. The head coach announced on Friday that the Hyde's availability against the Cardinals will be a game-time decision.

The 49ers offense have leaned heavily on Hyde and the run game. Hyde's 253 rushing yards ranks third in the NFL behind only Kareem Hunt (401) and Dalvin Cook (288).

San Francisco and Arizona have faced off 51 times. Here are the best shots from the teams' meetings.

If Hyde is unable to play on Sunday, it will be a combination of Matt Breida and Raheem Mostert in the backfield against Arizona's 10th-ranked run defense.

Jaquiski Tartt, Kyle Juszczyk and Brock Coyle, all of whom suffered concussions against the Rams, should be good to go on Sunday. They're officially listed as questionable, but all three have shed the blue non-contact jersey at practice.

"I'm optimistic that they will go," Shanahan said. "When it comes to concussions, my experience with it is, I don't ever try to totally predict. Things can change, and you never totally know what to expect. And you have to be very safe with that stuff also."

Reuben Foster will make the trip to Arizona, however he will not be active in Sunday's contest. Although Foster has not been a participant in practice, he has been making great strides in his rehab. The rookie, who suffered a high-ankle sprain in Week 1, has been seen engaging in light running and workouts throughout the week.

As far as the Cardinals, defensive tackle Robert Nkemdiche (calf) and guards Alex Boone (chest) and Mike Iupati (tricep) are all listed as out for Sunday's contest. Tackle D.J. Humphries (knee) and wide receivers John Brown (quadricep) and J.J. Nelson (hamstring) are listed as questionable.

The complete list of inactive players will be released 90 minutes prior to kickoff on Sunday. Stay tuned to 49ers.com for updates.

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