49ers vs. Patriots Matchup Information

History: 49ers at Patriots

  • San Francisco owns the overall series record vs. New England, 8-5, including a 4-3 record versus the Patriots on the road.
  • The 49ers will travel to New England for the first time since 2012, when they defeated the Patriots, 41-34, on NBC's Sunday Night Football.

Players and Coaches to Know: