Trey Sermon Dives Into the End Zone for First-Career TD

Watch all of 49ers running back Elijah Mitchell's top highlights from the rookie's 107-yard game against the Indianapolis Colts on "Sunday Night Football."

Watch the San Francisco 49ers top plays vs. the Indianapolis Colts during Week 7 of the NFL 2021 season.

49ers quarterback Jimmy Garoppolo connected with tight end Charlie Woerner for a 27-yard gain.

Quarterback Jimmy Garoppolo capped off the 49ers 70-yard drive with a 14-yard touchdown to wide receiver Deebo Samuel.

49ers defensive end Nick Bosa put pressure on Colts quarterback Carson Wentz and linebacker Azeez Al-Shaair picked off the pass and returned it for 12 yards.

Kicker Joey Slye put up three for the 49ers connecting on a 56-yard field goal.

49ers linebacker Fred Warner came up from the pile with the ball to end the Indianapolis Colts first drive.

Running back Elijah Mitchell closed out the 49ers first drive of "Sunday Night Football" with a touchdown.

49ers rookie running back Elijah Mitchell ran up the field full speed for a 20-yard pickup.

Watch some of the 49ers top highlights against the Arizona Cardinals in Week 5 of the 2021 NFL season.

Watch every play from 49ers rookie quarterback Trey Lance's first-career start in Week 5 of the 2021 season.

49ers wide receiver Deebo Samuel caught a pass from quarterback Trey Lance over his defender for 26 yards.

49ers wide receiver Brandon Aiyuk made a one-handed reception over his defender for 26 yards.

49ers wide receiver Deebo Samuel rushed for 13 yards and a touchdown.

49ers defensive back Dontae Johnson forced and then recovered a key fumble of Arizona Cardinals running back Chase Edmonds.

49ers wide receiver Mohamed Sanu Sr. caught a 6-yard pass from quarterback Trey Lance to convert on fourth down.

49ers fullback Kyle Juszczyk went up and over a would-be tackle to gain a first down.

49ers defensive end Nick Bosa sacked Arizona Cardinals quarterback Kyler Murray to move the Cardinals out of field goal range.

Quarterback Trey Lance looked downfield to wide receiver Deebo Samuel to move the chains.

49ers defensive tackle D.J. Jones recorded his first sack of the season against Cardinals quarterback Kyler Murray.

Watch some of the 49ers best highlights from the first quarter of the 2021 season.

Check out the 49ers best plays from the team's Week 4 matchup against the Seattle Seahawks.

Watch every play from 49ers rookie quarterback Trey Lance's second half performance vs. the Seattle Seahawks.

Watch every play from 49ers wide receiver Deebo Samuel's 156-yard game against the Seattle Seahawks from Week 4 of the 2021 NFL Season.

49ers wide receiver Deebo Samuel muscled through contact for his second touchdown of the day.