History: 49ers vs. Eagles
- San Francisco owns the overall series record vs. Philadelphia, 19-13-1, and is 9-8 at home.
- The Niners are hosting the Eagles on Sunday Night Football for the second time and the first since 2010.
- The 49ers have won two of the last three overall meetings against the Eagles.
- San Francisco hosts Philadelphia at Levi's® Stadium for the second time, having defeated the Eagles, 26-21, on September 28, 2014.
Players and Coaches to Know:
49ers
- Head Coach: Kyle Shanahan
- Quarterback: Jimmy Garoppolo
- Tight End: George Kittle
- Cornerback: Richard Sherman
Eagles
- Head Coach: Doug Pederson
- Quarterback: Carson Wentz
- Tight End: Zach Ertz
- Cornerback: Darius Slay
