The two franchises have met 65 times since 1950. San Francisco holds the edge with 37 wins.
Thirteen years after tallying his first NFL catch at Ford Field, Anquan Boldin's career came full circle on Sunday as he hauled in his 1,000th career reception at the same venue.
Boldin made history on the San Francisco 49ers first offensive snap of the afternoon against the Detroit Lions, when he caught a screen pass from Blaine Gabbert for a five-yard gain.
The wide receiver became the 13th player in NFL history to reach the milestone, joining the likes of Hall-of-Famers Jerry Rice, Cris Carter and Tim Brown. Boldin's close friend from his Arizona Cardinals playing days, Larry Fitzgerald, hit the 1,000-catch mark earlier this month. Boldin accomplished the feat in his 185th career game. Only four players have done it faster.
Boldin is in the midst of another strong campaign for San Francisco. Despite missing two games due to injury, Boldin leads the 49ers in receptions and receiving yards for the third consecutive year. The 35-year-old is scheduled to become a free agent this spring, but he said this week that he "definitely" wants to return to San Francisco in 2016.