From the Trenches: 49ers Light Up "Monday Night Football"

Llegó la hora de las finales en nuestras ligas de Fantasy Football y por eso, Miguel Pasquel nos trae los tips que necesitamos para salir con la victoria. Además, los picks de la semana, incluyendo el del partido de Sunday Night de nuestros San Francisco 49ers.

Go on the field with the San Francisco 49ers players during the team's 48-27 victory over the Indianapolis Colts.

San Francisco 49ers QB Brock Purdy meets with the media to discuss his thoughts from the Colts game, setting a rhythm on offense, and previews the team's Week 18 matchup against the Bears.

San Francisco 49ers head coach Kyle Shanahan and defensive coordinator Robert Saleh give injury updates, preview the Bears matchup, and how they're preparing for Week 17.

San Francisco 49ers players answered festive questions and got in the holiday spirit at Levi's® Stadium.

Jesús Zárate y Carlos Yustis comentan todo sobre la quinta victoria al hilo de los San Francisco 49ers, esta vez sobre los Indianapolis Colts. Además, los jugadores que fueron seleccionados a los Pro Bowl Games 2026.

Los San Francisco 49ers continúan con un buen paso al sumar la quinta victoria al hilo en este cierre de temporada regular. Esta es la reacción de Miguel Pasquel al Monday Night.

Get an inside view of the 49ers locker room following the team's Week 16 win over the Colts presented by Ticketmaster.

San Francisco 49ers QB Brock Purdy, TE George Kittle, RB Christian McCaffrey, T Trent Williams, and LB Dee Winters highlighted team chemistry, preparation, and the importance of staying focused as the 49ers look ahead to the playoffs.

Enrique Zárate Jr. y Jesús Zárate reaccionan a la gran noche de los San Francisco 49ers de visita en Indianapolis, los 5 Touchdowns de Brock Purdy y sus impresiones de las tres fases del equipo. Además, una entrevista especial con Skyy Moore.

San Francisco 49ers DL C.J. West reflected on his first-career sack and shared his reaction to the 49ers "Monday Night Football" win over the Indianapolis Colts, presented by Lexus.

San Fransisco TE George Kittle marked seven receptions for 115 yards and a TD vs. the Indianapolis Colts on "Monday Night Football."

San Francisco 49ers QB Brock Purdy threw a career-high five touchdown passes in his team's Week 16 win over the Indianapolis Colts.

San Francisco 49ers RB Christian McCaffrey racked up 146 total scrimmage yards and caught two touchdowns Monday Night vs. the Indianapolis Colts.

Watch the best plays by the San Francisco 49ers against the Indianapolis Colts in Week 16 of the 2025 NFL season.

San Francisco 49ers head coach Kyle Shanahan reflected on the 49ers journey this season, emphasizing consistency, leadership, and the players' ability to overcome injuries and adversity to secure a crucial win.

San Francisco 49ers LB Dee Winters intercepted Indianapolis Colts QB Philip Rivers and returned it 74 yards for a pick-six.

San Francisco DL Alfred Collins sacks Colts QB Philip Rivers, forcing a fumble that results in a 15-yard loss in the team's Week 16 matchup.

San Francisco 49ers RB Christian McCaffrey catches a 9-yard touchdown pass from QB Brock Purdy, marking his second TD of the night.

Hear from head coach Kyle Shanahan, defensive coordinator Robert Saleh, and quarterback Brock Purdy as they speak to the media ahead of the team's Week 17 matchup against the Chicago Bears.

San Francisco 49ers RB Christian McCaffrey raced out of the backfield for a 24-yard gain, marking his longest carry of the 2025 season.

San Francisco QB Brock Purdy throws his fourth touchdown of the night to WR Jauan Jennings.

San Francisco 49ers QB Brock Purdy delivered a precise 21-yard pass to WR Jauan Jennings as the 49ers move the ball downfield against Indianapolis.

San Francisco 49ers QB Brock Purdy completed a 23-yard pass to WR Skyy Moore in the team's Week 16 matchup.

San Francisco DT C.J. West bursts through the line to sack Colts QB Philip Rivers for an 8-yard loss.