Deebo Samuel Takes Off for a Big 45-yard Gain

Relive some of the best plays ever made by the 49ers legendary halfback.

Relive some of the best plays ever made by the 49ers all-time leading rusher.

Watch NFL Network's countdown of the top 10 highlight-reel plays made by 49ers rookie running back Elijah Mitchell during the 2021 season.

Watch NFL Network's countdown of the top 10 highlight-reel plays made by 49ers tight end George Kittle during the 2021 season.

Watch NFL Network's countdown of the top 10 highlight-reel plays made by 49ers quarterback Jimmy Garoppolo during the 2021 season.

Check out this countdown of the 10 best highlight-reel plays made by the 49ers during the 2021 NFL season.

Watch a countdown of the top plays made by 49ers "wide back" Deebo Samuel during the 2021 NFL season.

Take a look at some of the best plays ever made by Pro Football Hall of Fame defensive lineman and 49ers legend Bryant Young.

49ers fullback Kyle Juszczyk celebrated with tight end George Kittle after taking a pass from Vikings quarterback Kirk Cousins into the end zone.

Watch the top highlights from 49ers wide receiver Deebo Samuel in the NFC Championship Game.

Watch the 49ers top plays vs. the Los Angeles Rams from the 2021 NFC Championship Game.

49ers quarterback Jimmy Garoppolo connected with tight end George Kittle for a 16-yard touchdown reception.

49ers wide receiver Jauan Jennings converted on third down to set up a San Francisco scoring drive.

Rams quarterback Matthew Stafford was stuffed by the 49ers defense on a fourth down QB sneak.

49ers wide receiver Deebo Samuel weaved through the Rams defense to put San Francisco on the board in the NFC Championship.

49ers quarterback Jimmy Garoppolo connected with wide receiver Brandon Aiyuk to move San Francisco across midfield.

49ers safety Jimmie Ward located a deflected pass from Rams quarterback Matthew Stafford, stopping Los Angeles' scoring drive.

Watch the San Francisco 49ers best highlights vs. the Green Bay Packers during the Divisional Round matchup at Lambeau Field.

Watch the top highlights from the 49ers defense and special teams during San Francisco's Divisional Round win over the Green Bay Packers.

49ers kicker Robbie Gould kicked a 45-yard field goal to send the 49ers to the NFC Championship game.

49ers defensive lineman Jordan Willis blocked the Packers punt which was recovered by safety Talanoa Hufanga for a touchdown.

49ers defensive lineman Arik Armstead stopped the Packers drive in the red zone with a third-down sack.

49ers wide receiver Deebo Samuel ran through multiple defenders on a third-down pickup.

49ers quarterback Jimmy Garoppolo's third-down strike hit tight end George Kittle in stride for a 24-yard gain.

Wide receiver Deebo Samuel took the kickoff 45 yards to set up a 49ers scoring drive.