Deebo Samuel Takes Off for a Big 45-yard Gain

Watch the top plays from Garoppolo's 424-yard, four touchdown game in the 49ers 36-26 victory over the Arizona Cardinals.

Watch all the top highlights from San Francisco's ninth victory of the season.

Watch every catch from Samuel's eight reception, 134-yard day against the Arizona Cardinals in Week 11.

The Arizona Cardinals lateral attempt ends in with a D.J. Reed Jr. fumble recovery for a 49ers touchdown.

Newly signed defensive lineman Damontre Moore knocked the ball free from KeeSean Johnson's hands and Jaquiski Tartt recovered the fumble.

Garoppolo hit an open Wilson Jr. for a 25-yard game-winning touchdown.

Bourne hauled in the pass on the slant route to give the 49ers the lead.

Dwelley slipped by the defense and Garoppolo hit him in stride for his second touchdown of the game.

Coleman hauled in the pass from Jimmy Garoppolo and turned up field to pick up 37 yards.

Jimmy Garoppolo found Dwelley open in the back of the end zone for the tight end's first-career score.

James Jr. followed his blockers for a 57-yard catch-and-run that set up a 49ers touchdown.

Watch the top plays from the Week 10 "Monday Night Football" matchup against the Seattle Seahawks.

Greenlaw ended the Seahawks drive in overtime and set the 49ers up inside Seattle territory.

McLaughlin connects on a 47-yard field goal to force overtime.

After K'Waun Williams strip-sacked Russell Wilson, Warner forced out the loose ball, Buckner recovered it and took it all the way for a 49ers touchdown.

Williams knocks the ball loose and Buckner recovered.

Tartt stripped the ball from Metcalf late in the first half to deny a Seahawks scoring chance.

Jimmy Garoppolo connected with Bourne over the middle for a 10-yard touchdown to put the 49ers up 10-0 on "Monday Night Football."

Coleman followed his lead blocker Kyle Juszczyk to set the 49ers up in the red zone.

Jimmy Garoppolo connected with Samuel over the middle for a 30-yard pickup.

View the top plays from Garoppolo's 317-yard, four touchdown performance against the Arizona Cardinals on "Thursday Night Football."

Watch the best moments from Kittle's six catch, 79-yard, one touchdown performance in the 49ers 28-25 victory over the Cardinals.

Watch the top highlights from the 49ers victory over the Arizona Cardinals in Week 9.

Garoppolo stepped up in the pocket and connected with Dwelley on key third down conversion.

Garoppolo connected with the receiver on a perfect 22-yard pitch-and-catch.