Deebo Samuel Takes Off for a Big 45-yard Gain

Watch the top highlights from the 49ers victory over the Cincinnati Bengals in Week 2.

Wilson scored his second touchdown of the game to give the 49ers a 31-point lead.

Jimmy Garoppolo connected with an open Samuel in the end zone for the team's fourth touchdown of the day.

Alexander jumped the route and picked off Andy Dalton to set up the 49ers field goal drive to end the second half.

Wilson found his way into the end zone for a 2-yard touchdown to extend the 49ers lead to 21-7.

Breida shows off his elusiveness and carries it 34 yards into the red zone to set up the 49ers third touchdown of the day.

Mostert hauls in the screen pass and takes it all the way to the house to give the 49ers a 14-7 lead.

Garoppolo connected with Goodwin downfield for a 38-yard touchdown on the 49ers opening drive.

Watch the top highlights from the 49ers victory over the Tampa Bay Buccaneers in Week 1.

Witherspoon intercepts the Jameis Winston pass for the 49ers third pick on the day.

Bosa gets to Jameis Winston for the rookie's first sack of his NFL career.

Garoppolo found a wide open James Jr. downfield for the 49ers first touchdown of 2019.

Sherman intercepts the pass and takes it to the endzone for his first pick six as a member of the San Francisco 49ers.

Nzeocha comes down with the tipped ball for the defense's second forced turnover of the game.

Warner punched the ball out from Buccaneers tight end O.J. Howard and Blair III recovers the loose ball.

Watch the top highlights from the preseason matchup between the 49ers and the Chargers.

Walter jumped over the line to score his first career touchdown in the fourth quarter vs. the Chargers.

Nzeocha cut in front of the Chargers wide receiver for the 49ers second interception of the game.

Flannigan-Fowles undercut Chargers quarterback Easton Stick's deep ball for an interception.

Beathard completed a 21-yard touchdown pass to Bourne to cut the Chargers lead to 20-14 in the first half.

Wilson Jr. cut back and followed the lead block from quarterback C.J. Beathard to give the 49ers a 7-6 lead over the Los Angeles Chargers.

Watch the top highlights from the 49ers victory over the Kansas City Chiefs in preseason week 3.

Wilson Jr. follows his blockers into the end zone to extend the 49ers lead to 27-17.

Wilson Jr. uses his speed to outrun the Chiefs defense to the end zone to give the 49ers a 20-17 lead.

Breida laid out for a spectacular diving touchdown grab from Garoppolo to tie the score at 7.