General manager John Lynch held a conference call following the league-mandated roster deadline. The San Francisco 49ers have trimmed their roster down to 53 ahead of Saturday's 1 p.m. PT cut off, with more moves expected in the coming days. Here are nine takeaways as the 49ers continue to shape its lineup ahead of Week 1.

1. Jerick McKinnon

McKinnon was placed on season-ending Injured Reserved for the second year after re-aggravating his surgically repaired ACL. The running back will have another procedure on his knee, which will keep him out for the entirety of the season.

"We sought a lot of opinions on this, but ultimately, the decision was made that he needs to undergo another procedure," Lynch said on Saturday. "(Being) ready in eight weeks wasn't going to be an option. That decision was made for us. We're hopeful for Jerick that this one is successful. We believe it will be. There's a lot of good news about his knee. Unfortunately there were some mechanical issues that didn't allow him to play this year. That's rough because he played so diligently to get back and it was sad to see that not be able to take place. Jerick is a fighter and he won't be deterred right now."

2. Nick Mullens and C.J. Beathard

Three quarterbacks remain on the 49ers roster as of Saturday. Lynch admitted to fielding phone calls for his backup quarterbacks, however the 49ers refused to budge on their trade demands.

"In the last week, there was a lot of interest and a lot of conversations. That position to us is one that you set a price on and you stay firm on it," Lynch said. "While we had discussions we never deviated from what that price was and no one ever met it so we were happy to carry the three in. We feel like that is a great position to be in - the position of strength. Not that we weren't open to it but a certain price had to be met and it wasn't. So we go in happily with these three."

The 49ers will communicate who will backup Jimmy Garoppolo in 2019 with San Fracisco's quarterbacks on Monday.

3. Nick Bosa

Lynch provided good news for the 49ers first round pick. Bosa, who missed the entire preseason with an ankle injury, is likely to return to the field ahead of the 49ers season opener. There is no word yet on whether the defensive lineman will be available in Week 1 against the Tampa Bay Buccaneers, however expect the 49ers to assess Bosa's availability in the coming days.

"The clarity that we have on Nick is that he'll be ready for practice on Monday," Lynch said. "How that goes, we've seen that with some other circumstances this year in situations where a guy is looking really good and then you've got to go practice and you've got to go play. Particularly at Nick's position, where he plays against big bodies and you've got to be able to turn and all that. That's a big step. But he'll be ready for practice on Monday and we'll see where it goes from there.

4. Safe at Safety

The 49ers parted ways with Adrian Colbert, Marcell Harris and Antone Exum, all who were apart of San Francisco's safety rotation in 2018. The 49ers will rely on their versatility along the secondary in addition to Jaquiski Tartt, Tarvarius Moore and Jimmie Ward as they continue to tinker the roster over the coming days.

"We have a lot of versatility in our defensive backfield whether it's guys like Tarvarius (Moore) and Jimmie (Ward) who are playing safety that can play corner. Or guys like D.J. Reed Jr. playing corner that have some safety flex that gives us some flexibility," Lych said. "I don't think that's unreasonable to expect that we may be making a move to bolster that safety unit."

5. Azeez Al-Shaair 

The 49ers parted ways with Elijah Lee and David Mayo as Al-Shaair impressed enough in August to beat out several veterans in the linebacker battle. The undrafted rookie suffered a serious knee injury in 2018, however blew San Francisco's medical team away with his speedy rehab and preseason performance. Al-Shaair makes the only undrafted rookie to land on San Francisco's initial 53.

"We had to vet it with our medical people because he was coming off an ACL," Lynch said. "Actually, we had to slow Azeez down because his return was coming so quickly that our doctors and medical staff felt that maybe he was pushing (it). He did his pro day like three months after his ACL surgery, and so their advice was that we slow him down in his rehab. He did that. He got himself to where that wasn't an issue, and just played at a very high level.

"(Azeez) played at a very high level. We felt like we couldn't keep him off the team. We're keeping five linebackers and Azeez earned his way on to this roster and beat some really good football players. You talk about guys like (David) Mayo and LaRoy Reynolds that had really strong camps. But that tells you how really well Azeez played in our minds that he earned a spot on this 53."

6. Jason Verrett 

The 49ers saw enough in Verrett in the spring to keep him on San Francisco's initial 53-man roster. The 49ers are optimistic Verrett, who was dealing with an ankle injury, will be ready for Week 1.

"His recovery from his ankle injury is going very well and a strong possibility we'll have him for Week 1. That's' still in play," Lynch said. "We made a decision that Jason was worth carrying on to this roster and we're pleased with that."

7. K'Waun Williams 

The 49ers nickel corner is working his way back from a knee injury. According to Lynch, Williams' rehab has been "trending well" and a week of practices will tell a lot about his readiness for Week 1.

8. Trent Taylor and Jalen Hurd 

The 49ers kept seven receivers on its initial 53-man roster, however are likely to be without two heading into the season opener. Taylor is still recovering from a foot surgery, and the 49ers are assessing Hurd's back tightness. According to Lynch, Hurd's symptoms are "getting better" and the 49ers will have a better answer to his availability in the coming days.

9. Joshua Garnett

San Francisco closed the door on the potential return of former first round pick Joshua Garnett. Garnett appeared in 22 games with 11 starts over the last three seasons, with all of his starts coming during his rookie season. Garnett missed the entire 2017 season with a season-ending knee injury.

"He's had a rough time the last couple of years being available," Lynch said. "Anytime that we had extended time with him getting reps on the field, his ability started to come to the forefront. Unfortunately since we've been here, he hasn't had that extended time on a consistent basis. ...If he can have a run of health, he's got the ability to be a high-level starter. We haven't had that opportunity and he hasn't had that opportunity. We wish Josh well, and hopefully a new situation is a good thing for him. It's hard to see a guy like that go because you'd love to keep waiting, we just didn't feel like we could do that any longer."