After a decisive Week 1 victory over the upstart Minnesota Vikings, the San Francisco 49ers have dropped five of their last six games.
This week, however, the 49ers face a St. Louis Rams team that they have beaten 10 out of the last 14 times. One of those games resulted in a tie.
When San Francisco visited St. Louis last year on "Monday Night Football," the club overcame a 14-point deficit to win, 31-17.
Here are the experts' picks from around the web for the Week 7 clash between NFC West foes. Give us your predictions in the comment section below...
Elliot Harrison of NFL.com: Rams 27, 49ers 13
"This seems like a game where the 49ers could conceivably surprise us all. St. Louis has been known to lose winnable games in the past. The great elixir here is Todd Gurley, who, if you haven't caught on, is pulling an Odell Beckham Jr.: tearing up the league after a delayed start to Year 1. Over the past three games, Gurley has rushed for 433 yards at a staggering 6.4 yards per carry. The 49ers' run defense is ranked 20th, in case you were wondering. Winning allegedly cures everything -- will Colin Kaepernick get enough time in the pocket to do so?"
The San Francisco 49ers and the Los Angeles - and St. Louis - Rams have a long history, going back to 1950. Here are photos from the 49ers road trips.
Pete Schrager of Fox Sports:](http://www.foxsports.com/nfl/story/nfl-week-8-picks-oakland-raiders-miami-dolphins-new-england-patriots-102915)** Rams 30, 49ers 17
"I had the Rams going to the playoffs before the season started, and if they keep on playing like they did last Sunday, I'll be mentioning this more and more as the season progresses. I'm waiting for some team – any team – to stop Todd Gurley. I don't see the 49ers having much success in doing that this weekend."
Michael David Smith of Pro Football Talk: Rams 21, 49ers 7
"I love the young players on the Rams' defense, and I think their pass rush is going to cause Colin Kaepernick fits. The Rams will take an early lead and then grind it out with Todd Gurley."
USA TODAY's panel of seven experts: seven pick Rams, none pick 49ers
ESPN's panel of 13 experts: 13 pick Rams, none pick 49ers
CBS Sports' panel of eight experts: six pick Rams, two pick 49ers