View the top images from Peyton Manning's long career of playing against the San Francisco 49ers.
The football world will miss No. 18. Two-time Super Bowl winning quarterback Peyton Manning announced his retirement on Monday, leaving behind him a Hall-of-Fame résumé and a legacy that will not soon be forgotten.
Manning played against the San Francisco 49ers five times in the regular season. He posted a 3-2 record with 1,521 passing yards and nine touchdowns.
Members of the 49ers took to Twitter and shared their respect for Manning.