Talanoa Hufanga Intercepts Justin Herbert to Seal the 49ers Win

Watch the top highlights from San Francisco 49ers running back Christian McCaffrey's two-touchdown game vs. the Seattle Seahawks on Thanksgiving.

Watch the San Francisco 49ers top highlights vs. the Seattle Seahawks in Week 12 of the 2023 NFL season.

San Francisco 49ers quarterback Brock Purdy aired it out to wide receiver Brandon Aiyuk for a 28-yard touchdown against the Seattle Seahawks.

San Francisco 49ers defensive linemen Nick Bosa and Kevin Givens took down Seattle Seahawks quarterback Geno Smith during the team's Thanksgiving night matchup.

The San Francisco 49ers season-high sixth sack against the Seattle Seahawks secures the team's Week 12 win.

San Francisco 49ers defensive linemen Arik Armstead and Javon Hargrave got to Seattle Seahawks quarterback Geno Smith for a sack in the red zone.

San Francisco 49ers defensive lineman Nick Bosa took down Seattle Seahawks quarterback Geno Smith on the opening drive of the second half.

The San Francisco 49ers special teams unit recovered a loose football following a muffed punt by the Seattle Seahawks.

San Francisco 49ers defensive lineman Javon Hargrave sacked Seahawks quarterback Geno Smith to end Seattle's drive.

San Francisco 49ers running back Christian McCaffrey ran into the end zone for his second touchdown of the night against the Seattle Seahawks.

San Francisco 49ers running back Christian McCaffrey pushed into the end zone to extend the 49ers lead over the Seattle Seahawks.

San Francisco 49ers cornerback Ambry Thomas ended the Seattle Seahawks drive with a sideline interception.

San Francisco 49ers wide receiver Jauan Jennings moved the chains during the team's Thanksgiving game in Seattle.

San Francisco 49ers quarterback Brock Purdy connected with wide receiver Deebo Samuel on back-to-back deep shots in the first quarter of the team's Thanksgiving night matchup.

San Francisco 49ers wide receiver Deebo Samuel sprinted into the end zone to cap off the team's opening drive against the Seattle Seahawks.

San Francisco 49ers running back Christian McCaffrey ran up the middle for a 27-yard gain on the team's opening drive vs. the Seattle Seahawks.

Watch the San Francisco 49ers highlights from Week 11 of the 2023 NFL season against the Tampa Bay Buccaneers.

Watch the best plays from San Francisco 49ers running back Christian McCaffrey's 103-yard game vs. the Tampa Bay Buccaneers during Week 11 of the 2023 NFL season.

Watch every one of San Francisco 49ers wide receiver Brandon Aiyuk's catches from his 156-yard game vs. the Tampa Bay Buccaneers in Week 11 of the 2023 NFL season.

Watch some of the top highlights from San Francisco 49ers quarterback Brock Purdy's three-touchdown game vs. the Tampa Bay Buccaneers.

San Francisco 49ers safety Ji'Ayir Brown intercepted Tampa Bay Buccaneers quarterback Baker Mayfield during the team's Week 11 matchup.

San Francisco 49ers tight end George Kittle hauled in a 3-yard touchdown pass from quarterback Brock Purdy.

San Francisco 49ers quarterback Brock Purdy completed a 40-yard pass to wide receiver Deebo Samuel.

San Francisco 49ers quarterback Brock Purdy kept his eyes downfield to connect with wide receiver Brandon Aiyuk for a touchdown.

San Francisco 49ers wide receiver Brandon Aiyuk escaped defenders to move the team across midfield.