Brock Purdy: 'Take Care of Business'

San Francisco 49ers WR Jauan Jennings, DB Deommodore Lenoir, and S Jason Pinnock discussed the race for the NFC West's top seed and looked ahead to "Monday Night Football" against the Indianapolis Colts.

San Francisco 49ers QB Brock Purdy shared insights on his preparation that goes into each game, reflected on the importance of staying focused on executing the offense, and discussed the team's approach to tempo, decision-making, and maintaining discipline in high-pressure situations.

Three-time Super Bowl Champion, former San Francisco 49ers tight end Brent Jones joined "You've Got Mail" presented by Delta Dental to discuss his induction to the Edward J. DeBartolo Sr. 49ers Hall of Fame, share memories from the 49ers Super Bowl dynasty, and more.

Defensive coordinator Robert Saleh and offensive coordinator Klay Kubiak discussed the team's matchup prep, highlighted key contributions from veterans and young players, and shared how the 49ers are staying focused on controlling their playoff run.

Offensive lineman Jake Brendel sits down for an episode of "Cut Different" presented by Gillette for a fresh cut and real talk on humble beginnings, family, motivation, and becoming a professional athlete.

Quedan tres partidos en la temporada para los San Francisco 49ers y el camino final comienza este lunes por la noche cuando visiten a los Indianapolis Colts. Miguel Pasquel y Alfredo Gutiérrez comentan todo lo que hay que saber previo a este duelo importante.

JJ Stankevitz from the Indianapolis Colts previews Week 16 "Monday Night Football", with one-on-one interviews featuring San Francisco 49ers DL Clelin Ferrell and WR Jauan Jennings.

San Francisco 49ers TE George Kittle, RB Christian McCaffrey, and DL Keion White discussed the energy inside the locker room, shared the importance of December games, and described the team's mindset as the 49ers continue their push towards the postseason.

San Francisco 49ers head coach Kyle Shanahan highlighted Indianapolis' run defense, reflected on overcoming injuries, and emphasized a one-week-at-a-time approach with the playoffs on the line.

Estamos a un paso de las finales en las ligas de Fantasy Football y por eso no hay que bajar la guardia. Miguel Pasquel tiene los tips para consolidar el triunfo en las semifinales, y además, los picks de la semana incluyendo el último duelo como visitante de los San Francisco 49ers en la temporada regular cuando viajen a Indianapolis para enfrentarse a los Colts.

Step inside San Francisco 49ers Week 15 win over the Tennessee Titans, presented by Toyota.

NFL Insider Tom Pelissero breaks down the playoff clinching scenarios around the NFL in Week 16. San Francisco 49ers have a shot to clinch on "Monday Night Football" with a win.

Watch the NFL's official Week 16 game preview for Indianapolis Colts vs. San Francisco 49ers.

Join San Francisco 49ers LB Dee Winters on the Microsoft Surface as he breaks down his biggest plays, presented by Copilot.

Go on the field with the San Francisco 49ers players during the team's 37-24 victory over the Tennessee Titans.

Listen in as San Francisco 49ers Head Coach Kyle Shanahan was wired for sound during the team's Week 15 matchup against the Tennessee Titans.

Jesús Zárate y Carlos Yustis analizan todo sobre el partido de la Semana 15 entre los San Francisco 49ers y los Tennessee Titans, así como el camino a recorrer el resto de la temporada para asegurar un lugar en los Playoffs.

The 49ers Foundation and our 49ers PREP team partnered with legacy beneficiary Fresh Lifelines for Youth (FLY) to welcome in youth from the William F. James Boys Ranch and FLY's at-risk youth to Levi's® Stadium.

Sergeant First Class Takumi Abe visited from Hawaii and spent time with TE George Kittle at Levi's® Stadium, creating a memorable exchange before the Tennessee Titans game.

Miguel Pasquel nos comparte su opinión sobre la décima victoria de los San Francisco 49ers en la temporada al vencer por 37 a 24 a los Tennessee Titans.

Get an inside view of the 49ers locker room following the team's Week 15 win over the Titans presented by Ticketmaster.

Enrique Zárate Jr. y Jesús Zárate analizan todo lo que ocurrió en el partido entre los San Francisco 49ers y los Tennessee Titans, que terminó con marcador de 24-37, con el que se consigue la décima victoria de la campaña. Además, una entrevista especial con el novato de la línea ofensiva, Connor Colby.

San Francisco 49ers WR Jauan Jennings reflected on scoring touchdowns on his first two receptions, praised QB Brock Purdy's performance, and shared his message to the Faithful following the 49ers Week 15 win over the Tennessee Titans, presented by Lexus.

San Francisco 49ers QB Brock Purdy, TE George Kittle, and RB Christian McCaffrey broke down big plays, celebrated standout moments, and reflected on the collective effort that powered the 49ers to victory against the Titans

San Francisco 49ers head coach Kyle Shanahan discussed QB Brock Purdy's standout performance, reflected on key moments from the game, and shared insights on the team's dynamics and player contributions.