Kittle vs. Mathieu, Tartt vs. Kelce and other matchups to watch in the Super Bowl matchup between San Francisco and Kansas City. 

Staley vs. Smith, Kittle vs. Martinez and other matchups to watch in the NFC Title game between San Francisco and Green Bay. 

Kittle vs. Wagner, Warner vs. Wilson and other matchups to watch in the Week 17 divisional contest between San Francisco and Seattle.

Here are five key matchups that could decide the 49ers and Cardinals second contest of the season. 

Here are five key matchups that could decide the 49ers Week 2 clash against the Bengals.

The 2019 Men's NCAA Basketball Tournament is back and members of the San Francisco 49ers are ready to root for their respective Alma Maters.

Looking at the top notes from Lynch and Shanahan's year-end presser.

A look at all of the recipients for the franchise's annual awards.

Second-year players George Kittle and Solomon Thomas headline the 49ers standouts against the Bears in Week 16.

The 49ers offensive line put up their second-straight standout performance in primetime.

Shanahan provided notes on the 49ers offensive line, Marquise Goodwin and Jerick McKinnon from the annual NFL meetings.

Answering your questions on how free agency has affected the 49ers approach to the 2018 NFL Draft.

A look at the 49ers vision for McKinnon and Richburg in 2018 and beyond.

You asked, Breida answered. Get to know the 49ers running back in this fan Q&A.

Six members of the 49ers were named to PFF's "Team of the Week" following their Week 17 win over the Rams.

The 49ers have a new left guard, DeForest Buckner continues to play a high percentage of snaps and Jimmie Ward returns.

Bold predictions and narratives ahead of the 49ers Week 2 divisional matchup against the Seattle Seahawks.

The San Francisco 49ers will hope to have reinforcements for this weekend's road game against the Seattle Seahawks.

Shanahan has had time to review the film and he shared his assessment of the 49ers Week 1 performance.

The San Francisco 49ers opened the year with a loss at home to the Panthers and sustained a worrisome injury going forward.

Follow along here for notes and highlights as the 49ers open the season at home against the Carolina Panthers.

From injury updates to potential starters, Kyle Shanahan covered a lot during Wednesday's press conference.

There's much to discuss as the 49ers roster is down to 53 players and the team is preparing for Week 1 against the Panthers.

A look at the 49ers roster by position group now that the initial 53-man list has been established.

Relive the 2019 Week 14 matchup between the San Francisco 49ers and the New Orleans Saints with this full game replay brought to you by NFL Game Pass.

What was your favorite moment of the season? What's the running back room like? Jerick McKinnon caught up with members of the 49ers and various reporters to ask the hard-hitting questions at Super Bowl LIV Opening Night.

NFL Network's Brian Baldinger analyzes the 49ers record-breaking rushing performance in their win against the Green Bay Packers in the NFC Championship game.

Watch the best plays from Jimmy Garoppolo and Co. during the 2019 regular season.

Go on the 49ers sideline with Kwon Alexander, George Kittle, Jimmy Garoppolo and the rest of the team during the Week 17 win over the Seattle Seahawks.

The 49ers teamed up with Martha's Kitchen to serve a Thanksgiving dinner to those in need.

Keiana Martin and Laken Tomlinson recapped the team's victory over the Redskins, broke down a few pivotal plays from Washington and previewed the Week 8 matchup against the Carolina Panthers.

Laken Tomlinson and Keiana Martin broke down 49ers defensive performance against the Redskins in Week 7.

Laken Tomlinson analyzed the explosive plays by the 49ers offense and the team celebration in this week's ORIG3N DNA of a Play.

The 49ers held a fashion show featuring guests representing all cancers who have either battled or are currently battling cancer as they modeled apparel donated by Levi's® alongside 49ers players.

Hear Nick Bosa, C.J. Beathard, Nick Mullens and Laken Tomlinson discuss the team's cut day and the start of the regular season.