Thompson (6-0, 175) originally entered the NFL after signing with the Houston Texans as an undrafted free agent on May 16, 2017. He was waived by Houston on September 2, 2017 and signed to the team's practice squad the following day. He was promoted to the Texans active roster on September 27, 2017 and went on to appear in 13 games and register five receptions for 84 yards in addition to six tackles on special teams. In 2018, he spent the majority of training camp with the Texans prior to being waived on August 28, 2018.
A 25-year-old native of Gainesville, FL, Thompson attended the University of Florida, where he appeared in 41 games (three starts) and registered nine receptions for 78 yards on offense in addition to 16 kickoff returns for 355 yards on special teams.