James Cregg is in his first season as a 49ers assistant offensive line coach. He joined the 49ers after spending after spending three seasons (2018-20) as the offensive line coach at Louisiana State University.
In 2020 with LSU, Cregg saw the Tigers rush for an average of 121.7 yards per game. The year prior, LSU had eight players start along the offensive line with the Tigers using a different starting lineup on the offensive line in consecutive games until games 8 and 9 in wins over Auburn and Alabama. C Lloyd Cushenberry, who was later drafted in the third round of the 2020 NFL Draft by the Denver Broncos, and RG Damien Lewis, who was later drafted in the third round of the 2020 NFL Draft by the Seattle Seahawks, started every game for the Tigers and both earned All-America honors. LSU's offensive line in 2019 helped pave the way for the first offense in NCAA history to feature a 5,000-yard passer, two 1,000-yard receivers and a 1,000-yard rusher. LSU's offense led the country in both scoring (32.0) and total offense (433.9) and set numerous SEC and school records on its way to a 15-0 record and a national title.