DeMeco Ryans is in his fourth season with the 49ers and third as the team's inside linebackers coach. He served as the team's defensive quality control coach in 2017.
In 2019, Ryans helped guide San Francisco's defense which ranked second in the NFL in total yards allowed per game (281.8), the fewest total yards allowed per game by the team since 1997 (250.8). The 49ers defense also ranked first in the NFL in forced fumbles (21) and sixth in takeaways (27). LB Fred Warner started all 16 games and led the team with 118 tackles, while also adding 3.0 sacks, one interception (returned for a touchdown), three forced fumbles, one fumble recovery and nine passes defensed.